Mathematical biology and pharmacology models have a long and rich history in the fields of
medicine and physiology, impacting our understanding of disease mechanisms and the …

Stem cell therapies are becoming a major topic in biomedical research all over the planet. It
may be a viable treatment choice for people suffering from a wide range of illnesses and …

Developing and improving mechanism-oriented computational models to better explain
biological phenomena is a dynamic and expanding frontier. As the complexity of targeted …

Gaucher's disease type 1 (GD1) leads to significant morbidity and mortality through clinical
manifestations, such as splenomegaly, hematological complications, and bone disease …

Quantitative Systems Pharmacology (QSP) modeling is increasingly used as a quantitative
tool for advancing mechanistic hypotheses on the mechanism of action of a drug, and its …

Linear-In-Flux-Expressions (briefly LIFE) methodology models metabolism by using
correlations among fluxes of metabolic networks and reducing the number of model …

In a recent paper [9] the authors introduced a new methodology for the simulation and
control of large metabolic systems called LIFE (Linear-in-Flux-Expressions). In many …

This review paper contains examples of population modeling that were collected through
self introductions sent to the population modeling mailing list. It is the third review this group …

Biological systems are inherently dynamic. Examples of dynamic networks are 1.)
interactions of metabolites in metabolic networks, 2.) cycling and entrainment of biological …

Biological phenomena at different scales such as 1. The metabolism of an organism (the
nano scale), 2. Cell proliferation and differentiation (the micro scale), and 3. Selective local …