Peptic ulcer disease

A Lanas, FKL Chan - The Lancet, 2017 - thelancet.com
The rapidly declining prevalence of Helicobacter pylori infection and widespread use of
potent anti-secretory drugs means peptic ulcer disease has become substantially less …

Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality

JY Lau, J Sung, C Hill, C Henderson, CW Howden… - Digestion, 2011 - karger.com
Abstract Background/Aims: The incidence of uncomplicated peptic ulcer has decreased in
recent years. It is unclear what the impact of this has been on the epidemiology of peptic …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Peptic ulcer disease

E Sverdén, L Agréus, JM Dunn, J Lagergren - Bmj, 2019 - bmj.com
Peptic ulcer disease presents with gastrointestinal symptoms similar to dyspepsia and can
be difficult to distinguish clinically. It can have potentially serious complications such as …

Epidemiology and diagnosis of acute nonvariceal upper gastrointestinal bleeding

G Rotondano - Gastroenterology Clinics, 2014 - gastro.theclinics.com
UGIB is predominantly nonvariceal in origin and remains one of the most common
challenges faced by gastroenterologists and endoscopists in daily clinical practice. Despite …

Helicobacter pylori‐negative duodenal ulcer disease

JP Gisbert, X Calvet - Alimentary pharmacology & therapeutics, 2009 - Wiley Online Library
Aliment Pharmacol Ther 30, 791–815 Summary Background Helicobacter pylori infection
rates in duodenal ulcer (DU) patients may be lower than previously estimated. Aim To …

Effects of Helicobacter pylori infection on long-term risk of peptic ulcer bleeding in low-dose aspirin users

FKL Chan, JYL Ching, BY Suen, YK Tse, JCY Wu… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Current guidelines recommend testing for Helicobacter pylori
infection among users of low-dose aspirin (ASA) who are at high risk for developing ulcers …

High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori–negative idiopathic bleeding ulcers

GLH Wong, VWS Wong, Y Chan, JYL Ching, K Au… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The long-term prognosis of peptic ulcers associated with neither
Helicobacter pylori nor nonsteroidal anti-inflammatory drugs (NSAIDs) is unknown …

Peptic ulcer disease: one in five is related to neither Helicobacter pylori nor aspirin/NSAID intake

C Charpignon, B Lesgourgues… - Alimentary …, 2013 - Wiley Online Library
Background The proportion (and even the reality) of peptic ulcer disease (PUD) not related
to H. pylori or NSAID/aspirin is debated. Aim To analyse the current epidemiological and …

Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding

GLH Wong, AJ Ma, H Deng, JYL Ching… - Alimentary …, 2019 - Wiley Online Library
Background Patients with a history of Helicobacter pylori–negative idiopathic bleeding
ulcers have an increased risk of recurring ulcer complications. Aim To build a machine …