Age-related macular degeneration

CJ Thomas, RG Mirza, MK Gill - Medical Clinics, 2021 - medical.theclinics.com
Background AMD involves pathologic changes to the deeper retinal layers of the macula
and surrounding vasculature resulting in central vision loss. The accumulation of retinal …

[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy

Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

[PDF][PDF] Disparities in vision health and eye care

AR Elam, VL Tseng, TM Rodriguez, EV Mike… - Ophthalmology, 2022 - Elsevier
Conclusions As we continue on the journey of addressing disparities in eye care and vision
health, it is imperative to know where we currently stand to move our field forward in an …

Critical review: vegetables and fruit in the prevention of chronic diseases

H Boeing, A Bechthold, A Bub, S Ellinger… - European journal of …, 2012 - Springer
Background Vegetables and fruit provide a significant part of human nutrition, as they are
important sources of nutrients, dietary fibre, and phytochemicals. However, it is uncertain …

Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

[HTML][HTML] The challenges and promise of complement therapeutics for ocular diseases

DH Park, KM Connor, JD Lambris - Frontiers in Immunology, 2019 - frontiersin.org
Ocular inflammation is a defining feature of sight threating diseases and its dysregulation
can catalyze and or propagate ocular neurodegenerative maladies such as age-related …

The pathophysiology of geographic atrophy secondary to age-related macular degeneration and the complement pathway as a therapeutic target

DS Boyer, U Schmidt-Erfurth… - Retina, 2017 - journals.lww.com
Purpose: Geographic atrophy (GA) is an advanced, vision-threatening form of age-related
macular degeneration (AMD) affecting approximately five million individuals worldwide. To …

Age-related macular degeneration preferred practice pattern®

CJ Flaxel, RA Adelman, ST Bailey, A Fawzi, JI Lim… - …, 2020 - aaojournal.org
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …

Age-related macular degeneration

M Fleckenstein, TDL Keenan, RH Guymer… - Nature reviews Disease …, 2021 - nature.com
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …