The key players in transcriptional regulation are transcription factors (TFs), proteins that bind
specific DNA sequences. Several mechanisms exist to turn TFs 'on'and 'off', including ligand …

Since the removal of thiazolidinediones (TZDs) from the market, researchers have been
exploring alternative anti-diabetic drugs that target PPARγ without causing adverse effects …

Peroxisome proliferator-activated receptor γ (PPAR γ) antagonists are a key instrument of
insulin sensitizers since they have the ability to sensitize insulin and can avoid adverse …

People with diabetes are at significantly higher risk of developing heart failure. Diabetic
cardiomyopathy describes heart disease in patients with diabetes who have no other …

Obesidade é uma patologia caracterizada pelo acúmulo de tecido adiposo em proporções
que afetam a saúde dos indivíduos e tem atingido proporções epidêmicas no mundo. Esses …