Mesenchymal stem/stromal cells (MSCs) are widely distributed in the body and play
essential roles in tissue regeneration and homeostasis. MSCs can be isolated from …

Periodontitis is one of the most common dental diseases. Compared with healthy
periodontal tissues, the immune microenvironment plays the key role in periodontitis by …

Periodontitis is the primary cause of tooth loss, but there is no effective treatment to repair
inflammatory bone loss in periodontitis. Exosomes emerge as essential paracrine factors of …

Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the
tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and …

In modern medicine, bone and dental loss and defects are common and widespread
morbidities, for which regenerative therapy has shown great promise. Mesenchymal stem …

Human mesenchymal stem cells (hMSCs) are multipotent cells, which exhibit plastic
adherence, express specific cell surface marker spectrum, and have multi‐lineage …

Background Periodontitis, which progressively destroys tooth-supporting structures, is one of
the most widespread infectious diseases and the leading cause of tooth loss in adults …

Recently, numerous types of human dental tissue-derived mesenchymal stem cells (MSCs)
have been isolated and characterized, including dental pulp stem cells, stem cells from …

Mandibular defect becomes a prevalent maxillofacial disease resulting in mandibular
dysfunctions and huge psychological burdens to the patients. Considering the routine …

Periodontal ligament stem cells (PDLSCs), which reside in the perivascular space of the
periodontium, possess characteristics of mesenchymal stem cells and are a promising tool …