Dynamic DNA methylation turnover at the exit of pluripotency epigenetically primes gene regulatory elements for hematopoietic lineage specification
Epigenetic mechanisms govern developmental cell fate decisions, but how DNA methylation
coordinates with chromatin structure and three-dimensional DNA folding to enact cell-type …
coordinates with chromatin structure and three-dimensional DNA folding to enact cell-type …
[HTML][HTML] MLL3/MLL4 enzymatic activity shapes DNA replication timing
Mammalian genomes are replicated in a precise order during S phase, which is cell-type-
specific 1–3 and correlates with local transcriptional activity 2, 4–8, chromatin modifications …
specific 1–3 and correlates with local transcriptional activity 2, 4–8, chromatin modifications …