Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5+ B cells that is characterized
by the accumulation of small, mature-appearing lymphocytes in the blood, marrow and …

Monoclonal B lymphocytosis (MBL) is defined as the presence of a clonal B-cell population
in the peripheral blood with fewer than 5× 109/L B-cells and no other signs of a …

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among the adults in
the Western World. CLL (and the corresponding nodal entity small lymphocytic lymphoma …

Clonally expanded blood cells that contain somatic mutations (clonal haematopoiesis) are
commonly acquired with age and increase the risk of blood cancer,,,,,,,–. The blood clones …

Our understanding of familial predisposition to lymphoma (collectively defined as non-
Hodgkin lymphoma [NHL], Hodgkin lymphoma [HL], and chronic lymphocytic leukemia …

Genome-wide association studies (GWAS) have previously identified 13 loci associated with
risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify …

We conducted a joint (pooled) analysis of three genome-wide association studies (GWAS),,
of esophageal squamous cell carcinoma (ESCC) in individuals of Chinese ancestry (5,337 …

Cancer development is a complex process driven by inherited and acquired molecular and
cellular alterations. Prevention is the holy grail of cancer elimination, but making this a reality …

Non-Hodgkin lymphoma (NHL) consists of many histologically and biologically distinct
lymphoid malignancies with poorly understood, but possibly distinct, etiologies. The patterns …

Chronic lymphocytic leukemia (CLL) can be familial; however, thus far no rare germ line
disruptive alleles for CLL have been identified. We performed whole-exome sequencing of …