Molecular insights of human skin epidermal and dermal aging

T Quan - Journal of Dermatological Science, 2023 - Elsevier
Human skin is the most widespread and abundant type of tissue in the human body. With the
passage of time, most of our organs, including a substantial part of the skin, tend to undergo …

Skin aging from the perspective of dermal fibroblasts: The interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous …

GJ Fisher, B Wang, Y Cui, M Shi, Y Zhao… - Journal of Cell …, 2023 - Springer
This article summarizes important molecular mechanisms that drive aging in human skin
from the perspective of dermal fibroblasts. The dermis comprises the bulk of the skin and is …

Cellular senescence as the causal nexus of aging

N Bhatia-Dey, RR Kanherkar, SE Stair… - Frontiers in …, 2016 - frontiersin.org
In this paper we present cellular senescence as the ultimate driver of the aging process, as a
“causal nexus” that bridges microscopic subcellular damage with the phenotypic …

Human skin aging and the anti-aging properties of retinol

T Quan - Biomolecules, 2023 - mdpi.com
The skin is the most-extensive and-abundant tissue in the human body. Like many organs,
as we age, human skin experiences gradual atrophy in both the epidermis and dermis. This …

The dark side of daylight: photoaging and the tumor microenvironment in melanoma progression

A Worrede, SM Douglass… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Continued thinning of the atmospheric ozone, which protects the earth from damaging
ultraviolet radiation (UVR), will result in elevated levels of UVR reaching the earth's surface …

[HTML][HTML] Age-associated increase in skin fibroblast–derived prostaglandin E2 contributes to reduced collagen levels in elderly human skin

Y Li, D Lei, WR Swindell, W Xia, S Weng, J Fu… - Journal of Investigative …, 2015 - Elsevier
Production of type I collagen declines during aging, leading to skin thinning and impaired
function. Prostaglandin E 2 (PGE 2) is a pleiotropic lipid mediator that is synthesized from …

Skin antiaging effects of a multiple mechanisms hyaluronan complex

F Chen, X Guo, Y Wu - Skin Research and Technology, 2023 - Wiley Online Library
Objective Intrinsic skin aging is an inevitable process with reduced extracellular matrix
deposition and impaired mechanical integrity in the dermal‐epidermal junction (DEJ) …

The Fatty Acid Compositions, Irritation Properties, and Potential Applications of Teleogryllus mitratus Oil in Nanoemulsion Development

W Chaiyana, J Inthorn, S Somwongin… - Nanomaterials, 2024 - mdpi.com
This study aimed to characterize and investigate the potential of the oils from Gryllus
bimaculatus, Teleogryllus mitratus, and Acheta domesticus to be used in nanoemulsions …

Nanoemulsions Containing Mucuna pruriens (L.) DC. Seed Extract for Cosmetic Applications

S Chookiat, T Theansungnoen, K Kiattisin, A Intharuksa - Cosmetics, 2024 - mdpi.com
Mucuna pruriens is a medicinal plant whose seeds have various types of pharmacological
activities and are used in many traditional medicines. The aim of this study was to evaluate …

Morphological, structural and biophysical properties of French and Brazilian photoaged skin

DG Mercurio, R Jdid, F Morizot… - British Journal of …, 2016 - academic.oup.com
Background Knowledge of skin biology and its alterations in different populations is very
important for the development of appropriate skincare strategies. Objectives To evaluate and …