Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: novel targets for therapy
LM Khachigian, BL Black, P Ferdinandy… - Vascular …, 2022 - Elsevier
Vascular smooth muscle cells (SMC) possess a unique cytoplasticity, regulated by
transcriptional, translational and phenotypic transformation in response to a diverse range of …
transcriptional, translational and phenotypic transformation in response to a diverse range of …
Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis
J Yao, L Cai, Y Chen, J Zhang, W Zhuang… - Cell Communication and …, 2022 - Springer
Cardiovascular disease is one of the leading causes of human mortality worldwide, mainly
due to atherosclerosis (AS), and the phenotypic transition of vascular smooth muscle cells …
due to atherosclerosis (AS), and the phenotypic transition of vascular smooth muscle cells …
Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis Corrigendum in/10.3892/ijmm. 2023.5267
X Liu, Y Wu, Z Zhou, M Huang… - International …, 2019 - spandidos-publications.com
Celecoxib, a selective cyclooxygenase‑2 inhibitor, has chemo‑preventive activity against
different cancer types, including bladder cancer (BC). However, the mechanisms by which …
different cancer types, including bladder cancer (BC). However, the mechanisms by which …
c‐Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR‐145‐5p/SPOP/PD‐L1 axis
L Zhang, X Wang, Y Li, J Han, X Gao… - Clinical and …, 2021 - Wiley Online Library
Esophageal adenocarcinoma (EAC), a subtype of esophageal carcinoma, is a severe health
problem associated with high death rate and poor prognosis. Immunotherapy has proven to …
problem associated with high death rate and poor prognosis. Immunotherapy has proven to …
miR579-3p is an inhibitory modulator of neointimal hyperplasia and transcription factors c-MYB and KLF4
Neointimal hyperplasia (IH) is a common vascular pathology that typically manifests in in-
stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic …
stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic …
Hsa‐miRNA‐143‐3p regulates the odontogenic differentiation of human stem cells from the apical papilla by targeting NFIC
Aim To evaluate the effects of hsa‐miRNA‐143‐3p on the cytodifferentiation of human stem
cells from the apical papilla (hSCAPs) and the post‐transcriptional regulation of Nuclear …
cells from the apical papilla (hSCAPs) and the post‐transcriptional regulation of Nuclear …
Biomarkers in VSMC phenotypic modulation and vascular remodeling
Y Qi, F Dai, J Gu, W Yao - Die Pharmazie-An International …, 2019 - ingentaconnect.com
Vascular smooth muscle cells (VSMCs) are not terminally differentiated and can change
their phenotype in response to environmental cues. Phenotype switching of VSMCs to less …
their phenotype in response to environmental cues. Phenotype switching of VSMCs to less …
[HTML][HTML] Transforming Cardiotoxicity Detection in Cancer Therapies: The Promise of MicroRNAs as Precision Biomarkers
I Moscoso, M Rodríguez-Mañero… - International Journal of …, 2024 - mdpi.com
Cardiotoxicity (CDTX) is a critical side effect of many cancer therapies, leading to increased
morbidity and mortality if not addressed. Early detection of CDTX is essential, and while …
morbidity and mortality if not addressed. Early detection of CDTX is essential, and while …
Exosomes and lipid metabolism in metabolic and cardiovascular disorders
ZZ Abdin, AZ Geng, M Chandy - Current Opinion in Lipidology, 2023 - journals.lww.com
Recent advances in our understanding of exosomes and lipid metabolism have implications
for our understanding of normal cellular and physiological functions as well as disease …
for our understanding of normal cellular and physiological functions as well as disease …
A tangled tale of microRNA and cardiac fibrosis
M Chandy - Clinical Science, 2019 - portlandpress.com
Cardiac fibrosis is important for wound healing, regeneration and producing the extracellular
matrix (ECM) that provides the scaffold for cells. In pathological situations, fibroblasts are …
matrix (ECM) that provides the scaffold for cells. In pathological situations, fibroblasts are …