Valvular heart disease is a leading cause of cardiovascular morbidity and mortality and a
major contributor of symptoms and functional disability. Knowledge of valvular heart disease …

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment
options for individuals with a given medical condition. Perhaps the most essential feature of …

We systematically reviewed the literature to ascertain how well clinicians determine the
probability and type of left-sided heart failure in their patients. Left-sided heart failure is …

Because of conflicting results from studies examining the usefulness of digoxin in congestive
heart failure (CHF) patients in sinus rhythm, a cross-over trial was conducted in which 20 …

Abstract purpose: To reappraise the effectiveness of digoxin for the treatment of congestive
heart failure (CHF) in patients with sinus rhythm in light of data from recently published …

Objective To determine whether nifedipine or prazosin is the more appropriate second‐line
antihypertensive agent in pregnancy. Design Randomised controlled trial. Setting Tygerberg …

After myocardial infarction, the renin-angiotensin system is found to be activated. While this
response may be beneficial in acute failure, it could be detrimental in chronic stages …

Myocardial infarction evokes major physiological changes because of the acute loss of
functional cardiac tissue, resulting in more or less severe symptoms of congestive heart …

Although the cardiac glycosides are universally acknowledged to be important agents in the
drug therapy of advanced congestive heart failure (CHF), their role in the treatment of more …

Adrenoceptors, or adrenergic receptors, can be defined as the cell receptors which respond
to the physiological agonists noradrenaline and adrenaline by producing a response in the …