Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application

AML Seca, DCGA Pinto - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …

Terpenoids' anti-cancer effects: Focus on autophagy

C El-Baba, A Baassiri, G Kiriako, B Dia, S Fadlallah… - Apoptosis, 2021 - Springer
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …

Lagerstroemia speciosa (L.) Pers. triggers oxidative stress mediated apoptosis via intrinsic mitochondrial pathway in HepG2 cells

RS Thakur, E Devaraj - Environmental Toxicology, 2020 - Wiley Online Library
Hepatocellular carcinoma is the second leading cause of cancer‐related mortality
worldwide. Lagerstroemia speciosa Pers.(Lythraceae) commonly known as Banaba has …

Ethanolic Extract of Lagerstroemia Speciosa (L.) Pers., Induces Apoptosis and Cell Cycle Arrest in HepG2 Cells

T Rohit Singh, D Ezhilarasan - Nutrition and cancer, 2020 - Taylor & Francis
Abstract Lagerstroemia speciosa (L.) Pers.,(Lythraceae) also called Banaba is a native plant
of southeast Asia and is widely used in traditional medicinal system. Herbal tea from banaba …

Targeting drug chemo-resistance in cancer using natural products

WH Talib, AR Alsayed, M Barakat, MI Abu-Taha… - Biomedicines, 2021 - mdpi.com
Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery

F Majolo, LKOB Delwing, DJ Marmitt… - Phytochemistry …, 2019 - Elsevier
Cancer is one of the largest causes of morbimortality in the world and due to its prevalence
the discovery of novel anticancer drugs in of great importance. The past century brought …

[HTML][HTML] Perspectives on natural compounds in chemoprevention and treatment of cancer: an update with new promising compounds

A Haque, D Brazeau, AR Amin - European Journal of Cancer, 2021 - Elsevier
Cancer is the second deadliest disease worldwide. Although recent advances applying
precision treatments with targeted (molecular and immune) agents are promising, the …

Paraptosis in the anti-cancer arsenal of natural products

D Lee, IY Kim, S Saha, KS Choi - Pharmacology & therapeutics, 2016 - Elsevier
Given the problems with malignant cancer cells showing innate and acquired resistance to
apoptosis, we need alternative means to induce cell death in cancer. Paraptosis is a type of …

Emerging cytotoxic alkaloids in the battle against cancer: Overview of molecular mechanisms

Z Habli, G Toumieh, M Fatfat, ON Rahal… - Molecules, 2017 - mdpi.com
Considered as the second deadliest disease globally, cancer has captured the attention of
researchers who have been trying with perseverance to decode its hidden aspects, to find …

Deep eutectic solvents and nonconventional technologies for blueberry-peel extraction: Kinetics, anthocyanin stability, and antiproliferative activity

G Grillo, V Gunjević, K Radošević, IR Redovniković… - Antioxidants, 2020 - mdpi.com
Interest in bioactive phytochemicals and sustainable processes is the driving force behind
this study on two novel green extraction methods for the recovery of anthocyanins from the …