Neutrophil extracellular traps (NETs) and damage‐associated molecular patterns (DAMPs): two potential targets for COVID‐19 treatment

S Cicco, G Cicco, V Racanelli… - Mediators of …, 2020 - Wiley Online Library
COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …

Neutrophil extracellular traps in cancer

L Cristinziano, L Modestino, A Antonelli… - Seminars in cancer …, 2022 - Elsevier
Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …

COVID‑19 and ischemic stroke: Mechanisms of hypercoagulability

S Zhang, J Zhang, C Wang… - International …, 2021 - spandidos-publications.com
During the coronavirus disease 2019 (COVID‑19) pandemic, some patients with severe
COVID‑19 exhibited complications such as acute ischemic stroke (AIS), which was closely …

A bittersweet response to infection in diabetes; targeting neutrophils to modify inflammation and improve host immunity

R Dowey, A Iqbal, SR Heller, I Sabroe… - Frontiers in …, 2021 - frontiersin.org
Chronic and recurrent infections occur commonly in both type 1 and type 2 diabetes (T1D,
T2D) and increase patient morbidity and mortality. Neutrophils are professional phagocytes …

Neutrophil extracellular traps, angiogenesis and cancer

R Poto, L Cristinziano, L Modestino, A de Paulis… - Biomedicines, 2022 - mdpi.com
Human neutrophils, the most abundant circulating leukocytes, are fundamental components
of the host response against different pathogens. Until a few years ago, neutrophils received …

Neutrophil extracellular traps and long COVID

A Shafqat, MH Omer, I Albalkhi… - Frontiers in …, 2023 - frontiersin.org
Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …

Identification of renal ischemia reperfusion injury subtypes and predictive strategies for delayed graft function and graft survival based on neutrophil extracellular trap …

J Wu, F Zhang, X Zheng, J Zhang, P Cao… - Frontiers in …, 2022 - frontiersin.org
Background Ischemia reperfusion injury (IRI) is an inevitable process in renal
transplantation, which is closely related to serious postoperative complications such as …

Neutrophil extracellular traps and neutrophil-derived mediators as possible biomarkers in bronchial asthma

G Varricchi, L Modestino, R Poto, L Cristinziano… - Clinical and …, 2022 - Springer
Neutrophils (PMNs) contain and release a powerful arsenal of mediators, including several
granular enzymes, reactive oxygen species (ROS) and neutrophil extracellular traps (NETs) …

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …

Neutrophil extracellular traps and pulmonary fibrosis: An update

S Yan, M Li, B Liu, Z Ma, Q Yang - Journal of Inflammation, 2023 - Springer
Pulmonary fibrosis (PF) is a serious and often fatal illness that occurs in various clinical
settings and represents a significant unmet medical need. Increasing evidence indicates that …