Central nervous system myelin is a dynamic entity arising from membrane processes
extended from oligodendrocytes, which form a tightly wrapped multilamellar structure …

The classic myelin basic protein (MBP) splice isoforms range in nominal molecular mass
from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in …

Myelin basic protein (MBP) binds to negatively charged lipids on the cytosolic surface of
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …

The degradation of myelin in the CNS is the hallmark of multiple sclerosis. Reduction in the
net positive charge of myelin basic protein (MBP), through deimination, correlates strongly …

The myelin sheath is a multilayered membrane in the nervous system, which has unique
biochemical properties. Myelin carries a set of specific high‐abundance proteins, the …

Multiple sclerosis (MS) is an inflammatory disease where phagocytic cells infiltrate the nerve
tissue and act as terminal agents in destruction of the myelin sheath. However, the …

The myelin basic protein (MBP) family comprises a variety of developmentally-regulated
members arising from different transcription start sites, differential splicing, and post …

Myelin basic protein (MBP) is a multifunctional protein involved in maintaining the stability
and integrity of the myelin sheath by a variety of interactions with membranes and with …

Cyanylated cysteine, or β-thiocyanatoalanine, is an artificial amino acid that can be
introduced into peptides and proteins by post-translational chemical modification of solvent …

The classic isoforms of myelin basic protein (MBP) are essential for the formation and
maintenance of myelin in the central nervous system of higher vertebrates. The protein is …