Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
MT Makale, CR McDonald… - Nature Reviews …, 2017 - nature.com
Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …
Microglia in cancer therapy-related cognitive impairment
EM Gibson, M Monje - Trends in neurosciences, 2021 - cell.com
Millions of cancer survivors experience a persistent neurological syndrome that includes
deficits in memory, attention, information processing, and mental health. Cancer therapy …
deficits in memory, attention, information processing, and mental health. Cancer therapy …
Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus
M Lambrecht, DBP Eekers, C Alapetite… - Radiotherapy and …, 2018 - Elsevier
Purpose For unbiased comparison of different radiation modalities and techniques,
consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose …
consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose …
Regional susceptibility to dose-dependent white matter damage after brain radiotherapy
M Connor, R Karunamuni, C McDonald… - Radiotherapy and …, 2017 - Elsevier
Background and purpose Regional differences in sensitivity to white matter damage after
brain radiotherapy (RT) are not well-described. We characterized the spatial heterogeneity …
brain radiotherapy (RT) are not well-described. We characterized the spatial heterogeneity …
[HTML][HTML] Clinical applications of magnetic resonance imaging based functional and structural connectivity
Advances in computational neuroimaging techniques have expanded the armamentarium of
imaging tools available for clinical applications in clinical neuroscience. Non-invasive, in …
imaging tools available for clinical applications in clinical neuroscience. Non-invasive, in …
Treatment of radiation‐induced brain necrosis
X Yang, H Ren, J Fu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Radiation‐induced brain necrosis (RBN) is a serious complication of intracranial as well as
skull base tumors after radiotherapy. In the past, due to the lack of effective treatment …
skull base tumors after radiotherapy. In the past, due to the lack of effective treatment …
Improved neuropsychological outcomes following proton therapy relative to X-ray therapy for pediatric brain tumor patients
JP Gross, S Powell, F Zelko, W Hartsell… - Neuro …, 2019 - academic.oup.com
Background Survivors of pediatric brain tumors are at risk for impaired development in
multiple neuropsychological domains. The purpose of this study was to compare …
multiple neuropsychological domains. The purpose of this study was to compare …
Advanced magnetic resonance imaging techniques in management of brain metastases
H Mehrabian, J Detsky, H Soliman, A Sahgal… - Frontiers in …, 2019 - frontiersin.org
Brain metastases are the most common intracranial tumors and occur in 20–40% of all
cancer patients. Lung cancer, breast cancer, and melanoma are the most frequent primary …
cancer patients. Lung cancer, breast cancer, and melanoma are the most frequent primary …
Regional responses in radiation-induced normal tissue damage
DC Voshart, J Wiedemann, P van Luijk, L Barazzuol - Cancers, 2021 - mdpi.com
Simple Summary Side effects caused by the concomitant irradiation of normal tissue during
radiotherapy for cancer treatment can negatively affect the patient's quality of life and limit …
radiotherapy for cancer treatment can negatively affect the patient's quality of life and limit …
Cognitive impairment and morphological changes after radiation therapy in brain tumors: a review
J Jacob, T Durand, L Feuvret, JJ Mazeron… - Radiotherapy and …, 2018 - Elsevier
Life expectancy of patients treated for brain tumors has lengthened due to the therapeutic
improvements. Cognitive impairment has been described following brain radiotherapy, but …
improvements. Cognitive impairment has been described following brain radiotherapy, but …