Trigeminal neuralgia: basic and clinical aspects

EI Araya, RF Claudino, EJ Piovesan… - Current …, 2020 - ingentaconnect.com
The trigeminal nerve is the largest of all cranial nerves. It has three branches that provide the
main sensory innervation of the anterior two-thirds of the head and face. Trigeminal …

Trigeminal neuralgia: toward a multimodal approach

A Spina, P Mortini, F Alemanno, E Houdayer… - World neurosurgery, 2017 - Elsevier
Objectives Trigeminal neuralgia (TN) is the most common cranial neuralgia in adults, with a
slight prevalence in women. Antiepileptic drugs represent the mainstay of the medical …

Optogenetic activation of dopamine receptor D1 and D2 neurons in anterior cingulate cortex differentially modulates trigeminal neuropathic pain

S Liu, H Shu, J Crawford, Y Ma, C Li, F Tao - Molecular neurobiology, 2020 - Springer
Anterior cingulate cortex (ACC) is a critical brain center for chronic pain processing.
Dopamine signaling in the brain has been demonstrated to contribute to descending pain …

Comparing percutaneous treatments of trigeminal neuralgia: 19 years of experience in a single centre

I Noorani, A Lodge, G Vajramani… - Stereotactic and …, 2016 - karger.com
Background: Glycerol rhizolysis, thermocoagulation, and balloon compression are well
established in the treatment of trigeminal neuralgia. Objective: To compare the outcome …

Design of phase 3 studies evaluating vixotrigine for treatment of trigeminal neuralgia

M Kotecha, WP Cheshire, H Finnigan… - Journal of Pain …, 2020 - Taylor & Francis
Purpose Vixotrigine (BIIB074) is a voltage-and use-dependent sodium channel blocker.
These studies will evaluate the efficacy and safety of vixotrigine in treating pain experienced …

Surgical and clinical outcomes of microvascular decompression: a comparative study between young and elderly patients

G Menna, A Rapisarda, A Izzo, M D'Ercole… - Brain Sciences, 2022 - mdpi.com
Microvascular decompression (MVD) is the only etiological technique for the treatment of
trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of …

Alexithymia and depression may predict treatment failure in patients undergoing Gamma Knife radiosurgery for trigeminal neuralgia: the potential contribution of …

Y Samanci, SSY Oner, S Peker - Journal of Neurosurgery, 2023 - thejns.org
OBJECTIVE Gamma Knife radiosurgery (GKRS) effectively achieves high rates of pain
control in trigeminal neuralgia (TN); however, psychological factors can also impact how …

The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in idiopathic trigeminal neuralgia patients

W Cui, X Yu, H Zhang - The journal of headache and pain, 2014 - Springer
Background To investigate the possible association between the serotonin transporter gene
(5-HTTLPR) and rs 25531 polymorphism and the susceptibility and the pain severity in …

[PDF][PDF] Gamma knife radiosurgery on the trigeminal root entry zone for idiopathic trigeminal neuralgia: results and a review of the literature

SH Park, JW Chang - Yonsei medical journal, 2020 - synapse.koreamed.org
Trigeminal neuralgia (TN) is a chronic disorder of the trigeminal nerve characterized by
repeated electrical shock-like sensations on one side of the face. It can cause severe pain in …

Evaluation of serum vitamin B12 levels and its correlation with clinical presentation in patients with trigeminal neuralgia

P Dhole, V Lohe, R Bhowate, SM Gondivkar… - Journal of Oral Biology …, 2022 - Elsevier
Background The objective of this study was to estimate serum vitamin B12 levels and its
correlation with severity of clinical presentation in patients with trigeminal neuralgia (TN) …