The serotonergic system extends throughout the central nervous system (CNS) and the
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …

Background Attention deficit hyperactivity disorder (ADHD) is a common
neurodevelopmental disorder in childhood. The psychostimulant methylphenidate is the …

Buspirone is an anxiolytic drug and is a partial agonist for the serotonin 5-HT1A receptors as
well as possessing low affinity and is an antagonist for the dopamine D2 autoreceptors, with …

The onset of attention-deficit-hyperactivity-disorder (ADHD) in childhood is characterized by
developmentally inappropriate levels of hyperactivity, impulsivity and inattention. A chronic …

Background Treatments for mental health problems in childhood and adolescence have
advanced in the last 15 years. Despite advances in research, most of the evidence on …

The aim of this study is to gather evidence of head-to-head double-blind randomized-
controlled trials on the efficacy and safety of available treatments for attention deficit …

Objectives: An increasing number of abandoned clinical trials have forestalled efforts to
advance the evidence base for the treatment of mood and anxiety disorders in children and …

Background To review empirical studies of adverse drug reactions (ADRs) reported to be
associated with the use of medications generally licensed for treatment of attention deficit …

Abstract Introduction Attention Deficit Hyperactivity Disorder (ADHD) is a
neurodevelopmental disorder with no clear etiopathogenesis. Owing to unique socio cultural …

The core symptoms of attention deficit hyperactivity disorder (ADHD) are due to the
hypofunction of the brain's adrenergic (NE) and dopamine (DA) systems. Drugs that …