The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies

CA Juan, JM Pérez de la Lastra, FJ Plou… - International journal of …, 2021 - mdpi.com
Living species are continuously subjected to all extrinsic forms of reactive oxidants and
others that are produced endogenously. There is extensive literature on the generation and …

Oxidative stress, testicular inflammatory pathways, and male reproduction

S Dutta, P Sengupta, P Slama… - International journal of …, 2021 - mdpi.com
Inflammation is among the core causatives of male infertility. Despite male infertility being a
serious global issue,“bits and pieces” of its complex etiopathology still remain missing …

Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019 - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management

E Barati, H Nikzad, M Karimian - Cellular and Molecular Life Sciences, 2020 - Springer
Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

[HTML][HTML] Male oxidative stress infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic male infertility

A Agarwal, N Parekh, MKP Selvam… - The world journal of …, 2019 - synapse.koreamed.org
Despite advances in the field of male reproductive health, idiopathic male infertility, in which
a man has altered semen characteristics without an identifiable cause and there is no …

Oxidative stress and male infertility

T Takeshima, K Usui, K Mori, T Asai… - Reproductive …, 2021 - Wiley Online Library
Abstract Background Between 30% and 80% of patients with male infertility produce
excessive reactive oxygen species (ROS) in their ejaculate even though the cause of male …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

Sperm selection for ICSI: do we have a winner?

D Baldini, D Ferri, GM Baldini, D Lot, A Catino… - Cells, 2021 - mdpi.com
In assisted reproductive technology (ART), the aim of sperm cells' preparation is to select
competent spermatozoa with the highest fertilization potential and in this context, the …