Tissue vs. plasma concentration profiles have been generated from a physiologically-based
pharmacokinetic model of monoclonal antibody (mAb). Based on the profiles, we …

Camelidae possess an unusual class of antibodies devoid of light chains. Nanobodies are
intact antigen-binding fragments that are stable, easily generated against different targets …

Introduction Determination of the target-binding fraction (TBF) of radiopharmaceuticals using
cell-based assays is prone to inconsistencies arising from several intrinsic and extrinsic …

Epidermal growth factor receptor (EGFR) is one of the major molecular targets for cancer
diagnosis and therapy. EGFR and EGFRvIII, mutated form of EGFR, have been identified as …

Scorpions represent a significant threat to humans and animals in various countries
throughout the world. Recently, we introduced Nanobodies (Nbs) to combat more efficiently …

In the present work, the gelatin/fibronectin affinity was evaluated using SPR, QCM and
radiolabelling. The results indicate that type A gelatin films possess a higher affinity for Fn …

The tumor specificity of JAA-F11, a novel monoclonal antibody specific for the Thomsen-
Friedenreich cancer antigen (TF-Ag-alpha linked), has been comprehensively studied by in …

Detection of antigen 14C5, involved in substrate adhesion and highly expressed on the
membrane of many carcinomas, including lung cancer, provides important diagnostic …

For gene-based therapeutic approaches that require transfection of specific cell targets in
vivo, it is important to design the delivery system to have optimized tissue distribution …

This study identifies and characterizes the antigen recognized by monoclonal antibody
(mAb) 14C5. We compared the expression of antigen 14C5 with the expression of eight …