Ethnopharmacological relevance Galla chinensis (GC), a traditional Chinese medicine
(TCM), has a wide range of pharmacological properties which have been widely used for …

Mulberry (Morus atropurpurea) has long been used to treat gastro-intestinal ailments;
however, the functional basis of its therapeutic effects remains unclear. The aim of this study …

Centella asiatica (CA) has been used by Ayurvedic medical practitioners in India for almost
3000 years. The neuropharmacological properties of CA and its constituents have been …

Constipation is the most common gastrointestinal complaint all over the world, and it is a risk
factor of colorectal cancer. In this study, the protective of Quercetin against loperamide …

Context: Quercetin (QCT) has been known as a potential therapeutic strategy for
gastrointestinal diseases because it contributes to the stabilization of mast cells, the …

From the beginning of lives on earth, nature is contributing different products to the system
constantly and endlessly. Plants synthesize a large number of organic compounds, which …

Several types of saponins and herbal plants containing saponins have been reported to
have anti-inflammatory or laxative activities. To verify the therapeutic effects of saponin …

This study investigated the laxative effects of phlorotannins (Pt) derived from Ecklonia cava
(E. cave) on chronic constipation by evaluating alterations in stool parameters …

CRISPR-Cas9-mediated leptin (Lep) knockout (KO) mice exhibited prominent phenotypes
for constipation, even though they were not compared with other model animals. This study …

Indirect evidence has determined the possibility that microplastics (MP) induce constipation,
although direct scientific proof for constipation induction in animals remains unclear. To …