Bordetella pertussis and vaccination: the persistence of a genetically monomorphic pathogen

FR Mooi - Infection, Genetics and Evolution, 2010 - Elsevier
Before childhood vaccination was introduced in the 1950s, pertussis or whooping cough
was a major cause of infant death worldwide. Widespread vaccination of children was …

Defining pertussis epidemiology: clinical, microbiologic and serologic perspectives

JD Cherry, E Grimprel, N Guiso… - The Pediatric …, 2005 - journals.lww.com
In the past decade, numerous sources have noted an increase in reported pertussis in
highly immunized populations. This has been accompanied by a perceived change in …

Adaptation of Bordetella pertussis to vaccination: a cause for its reemergence?

FR Mooi, IH Van Loo, AJ King - Emerging infectious diseases, 2001 - ncbi.nlm.nih.gov
In the Netherlands, as in many other western countries, pertussis vaccines have been used
extensively for more than 40 years. Therefore, it is conceivable that vaccine-induced …

Reemergence of pertussis in the highly vaccinated population of the Netherlands: observations on surveillance data.

HE de Melker, JF Schellekens… - Emerging infectious …, 2000 - ncbi.nlm.nih.gov
We analyzed pertussis reporting, death, hospitalization, and serodiagnostic data from 1976
to 1998 to help explain the cause of the 1996 pertussis outbreak in the Netherlands. The …

Newly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008–2010

S Octavia, V Sintchenko, GL Gilbert… - Journal of Infectious …, 2012 - academic.oup.com
Australia is experiencing a prolonged epidemic of pertussis that began in 2008. A total of
194 Bordetella pertussis isolates collected from 2008 through 2010 were typed by single …

Epidemiological Typing of Bordetella pertussis Isolates: Recommendations for a Standard Methodology

FR Mooi, H Hallander, CH Wirsing von König… - European Journal of …, 2000 - Springer
Pertussis is re-emerging in vaccinated populations, and to gain insight into the reasons for
this development population-based studies are necessary. Unfortunately, various …

Factors contributing to pertussis resurgence

Q He, J Mertsola - 2008 - Future Medicine
Despite extensive immunization, the disease pertussis remains one of the world's leading
causes of vaccine-preventable deaths. An estimated 50 million cases and 300,000 deaths …

Multilocus Sequence Typing of Bordetella pertussis Based on Surface Protein Genes

IHM van Loo, KJ Heuvelman, AJ King… - Journal of clinical …, 2002 - Am Soc Microbiol
Despite more than 50 years of vaccination, Bordetella pertussis has remained endemic in
The Netherlands, causing epidemic outbreaks every 3 to 5 years. Strain variation may play a …

Multiple-Locus Variable-Number Tandem Repeat Analysis of Dutch Bordetella pertussis Strains Reveals Rapid Genetic Changes with Clonal Expansion during the …

LM Schouls, HGJ Van Der Heide, L Vauterin… - Journal of …, 2004 - Am Soc Microbiol
Bordetella pertussis, the causative agent of whooping cough, has remained endemic in The
Netherlands despite extensive nationwide vaccination since 1953. In the 1990s, several …

Polymorphism of Bordetella pertussisIsolates Circulating for the Last 10 Years in France, Where a Single Effective Whole-Cell Vaccine Has Been Used for More than …

C Weber, C Boursaux-Eude, G Coralie… - Journal of clinical …, 2001 - Am Soc Microbiol
We compared Bordetella pertussis isolates collected in France over the last 10 years, the
vaccine strains used for more than 30 years, and isolates collected before the introduction of …