Phytosterols: From preclinical evidence to potential clinical applications

B Salehi, C Quispe, J Sharifi-Rad… - Frontiers in …, 2021 - frontiersin.org
Phytosterols (PSs) are plant-originated steroids. Over 250 PSs have been isolated, and
each plant species contains a characteristic phytosterol composition. A wide number of …

[HTML][HTML] β-Sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide, and its incidence continues to
increase yearly. Despite significant advances in research, the search for effective and …

[HTML][HTML] Value addition in sesame: A perspective on bioactive components for enhancing utility and profitability

N Pathak, AK Rai, R Kumari, KV Bhat - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Sesame seed is a reservoir of nutritional components with numerous beneficial effects along
with health promotion in humans. The bioactive components present in the seed include …

[HTML][HTML] Lycium barbarum: a traditional Chinese herb and a promising anti-aging agent

Y Gao, Y Wei, Y Wang, F Gao, Z Chen - Aging and disease, 2017 - ncbi.nlm.nih.gov
Lycium barbarum has been used in China for more than 2,000 years as a traditional
medicinal herb and food supplement. Lycium barbarum contains abundant Lycium …

Singlet oxygen generation in dark‐hypoxia by catalytic microenvironment‐tailored nanoreactors for NIR‐II fluorescence‐monitored chemodynamic therapy

T Chen, P Hou, Y Zhang, R Ao, L Su… - Angewandte …, 2021 - Wiley Online Library
Abstract Singlet oxygen (1O2) has a potent anticancer effect, but photosensitized generation
of 1O2 is inhibited by tumor hypoxia and limited light penetration depth. Despite the potential …

Analysis of phytosterols in foods

MJ Lagarda, G García-Llatas, R Farré - Journal of pharmaceutical and …, 2006 - Elsevier
Phytosterols are bioactive compounds, one of their most studied and outstanding properties
being their cholesterol-lowering activity. This explains the growing interest in the phytosterol …

Plant sterols: factors affecting their efficacy and safety as functional food ingredients

A Berger, PJH Jones, SS Abumweis - Lipids in health and disease, 2004 - Springer
Plant sterols are naturally occurring molecules that humanity has evolved with. Herein, we
have critically evaluated recent literature pertaining to the myriad of factors affecting efficacy …

The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years

PJD Bouic - Current Opinion in Clinical Nutrition & Metabolic Care, 2001 - journals.lww.com
Although plant sterols (phytosterols) were chemically described in 1922, their biological role
in human and animal health has been underestimated. Their ability to control cholesterol …

Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems

JA Boutin, M Liberelle, S Yous, G Ferry… - Journal of Pineal …, 2024 - Wiley Online Library
Melatonin is a small natural compound, so called a neuro‐hormone that is synthesized
mainly in pineal gland in animals. Its main role is to master the clock of the body, under the …

Potential uses and benefits of phytosterols in diet: present situation and future directions

J Quilez, P Garcia-Lorda, J Salas-Salvado - Clinical Nutrition, 2003 - Elsevier
Over the past decade, the possibility of using phytosterols as ingredients in functional foods
has led to numerous research studies in relation to their ability to reduce blood cholesterol …