GpsB links peptidoglycan synthases to other proteins that determine the shape of the
respiratory pathogen Streptococcus pneumoniae (pneumococcus; Spn) and other low‐GC …

Synthesis of capsular polysaccharide (CPS), an important virulence factor of pathogenic
bacteria, is modulated by the CpsBCD phosphoregulatory system in Streptococcus …

The bacterial PASTA kinase, IreK, is required for intrinsic cephalosporin resistance in the
Gram‐positive opportunistic pathogen, Enterococcus faecalis. IreK activity is enhanced in …

Bacteria possess diverse classes of signaling systems that they use to sense and respond to
their environments and execute properly timed developmental transitions. One widespread …

Staphylococcus saprophyticus is the leading Gram-positive cause of uncomplicated urinary
tract infections. Recent reports of increasing antimicrobial resistance (AMR) in S …

Transposon sequencing (Tn-seq) is a powerful genome-wide technique to assess bacterial
fitness under varying growth conditions. However, screening via Tn-seq in vivo is …

Vibrio cholerae is a common waterborne pathogen that can cause pandemic cholera in
humans. The bacterium with heavy metal-tolerant phenotypes is frequently isolated from …

Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely
engulfing their cells. This PG network is the main component of the bacterial cell wall, it …

Clostridioides difficile is the leading cause of postantibiotic diarrhea in adults. During
infection, the bacterium must rapidly adapt to the host environment by using survival …

The cytosol of eukaryotic host cells is an intrinsically hostile environment for bacteria.
Understanding how cytosolic pathogens adapt to and survive in the cytosol is critical to …