The stability of lipids and other metabolites in human body fluids ranges from very stable
over several days to very unstable within minutes after sample collection. Since the high …

The octadecanoids are a broad class of lipids consisting of the oxygenated products of 18-
carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the …

Oxylipins derived from the cyclooxygenase (COX) and lipoxygenase (LOX) pathways of the
arachidonic acid (ARA) cascade are essential for the regulation of the inflammatory …

Several oxylipins are regulators of inflammation. They are formed by enzymes such as
lipoxygenases or cyclooxygenases, but also stereorandomly by autoxidation. Reversed …

Evidence suggests beneficial effects of long‐chain n–3 polyunsaturated fatty acids (PUFAs)
in inflammatory diseases. However, the underlying mechanisms are still subject of research …

Objective: Cardiovascular disease, a major cause of mortality and morbidity, exhibits sexual
dimorphism since the onset of cardiovascular disease occurs later in women than in men …

Enzymatic and nonenzymatic oxidation of linoleic (LA) and α-linolenic acid (ALA) during
pressing and storage of plant oils leads to a variety of oxylipins. We pressed oils from …

Abstract Analysis of fatty acids (FA) in food and biological samples such as blood is
indispensable in modern life sciences. We developed a rapid, sensitive and comprehensive …

For decades, research on oxidation of linoleic acid (LA, C18: 2 n6) and α-linolenic acid
(ALA, C18: 3 n3) in plant oils has focused on autoxidatively formed and lipoxygenase …

Oxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly
on cytokines. Here, using a standardized whole-blood stimulation system, we characterized …