This article reviews the manifestations and risk factors associated with osteoporosis in
childhood, the definition of osteoporosis and recommendations for monitoring and …

Bone is an extremely dynamic and adaptive tissue, whose metabolism and homeostasis is
influenced by many different hormonal, mechanical, nutritional, immunological and …

Objective To determine the frequency of incident vertebral fractures (IVF) 12 months after
glucocorticoid (GC) initiation in children with rheumatic diseases and to identify children at …

Vertebral fractures are an important yet underrecognized manifestation of osteoporosis in
children with chronic, glucocorticoid‐treated illnesses. Our goal was to determine the …

Objective Vertebral fractures are an under‐recognized problem in children with inflammatory
disorders. We studied spine health among 134 children (87 girls) with rheumatic conditions …

Objective To summarize the published effects of systemic glucocorticoid therapy on bone
mineral density (BMD) and fractures in children. Methods We performed a systematic review …

Aromatase inhibitors (AIs), blockers of estrogen biosynthesis, delay bone maturation and
therefore are used increasingly to promote growth in children and adolescents with growth …

Duchenne muscular dystrophy (DMD) is an X‐linked recessive disorder characterized by
progressive muscle weakness, with eventual loss of ambulation and premature death. The …

Children with chronic illnesses such as Juvenile Idiopathic Arthritis and Crohn's disease,
particularly when taking glucocorticoids, are at significant risk for bone fragility. Furthermore …

Osteoporosis, a skeletal disorder characterized by compromised bone strength and an
increased risk of fractures, is an important paediatric disorder that involves almost all …