COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …

The role of Th17 response in COVID-19

D Martonik, A Parfieniuk-Kowerda, M Rogalska… - Cells, 2021 - mdpi.com
COVID-19 is an acute infectious disease of the respiratory system caused by infection with
the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2). Transmission …

[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?

A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …

The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

G Morris, CC Bortolasci, BK Puri, L Olive, W Marx… - Life sciences, 2020 - Elsevier
In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …

Contribution of STAT3 to the pathogenesis of COVID-19

A Jafarzadeh, M Nemati, S Jafarzadeh - Microbial pathogenesis, 2021 - Elsevier
Hyper-inflammatory responses, lymphopenia, unbalanced immune responses, cytokine
storm, large viral replication and massive cell death play fundamental roles in the …

Regulatory T cells and acute lung injury: cytokines, uncontrolled inflammation, and therapeutic implications

S Lin, H Wu, C Wang, Z Xiao, F Xu - Frontiers in immunology, 2018 - frontiersin.org
Acute respiratory distress syndrome/acute lung injury (ALI) was described in 1967. The
uncontrolled inflammation is a central issue of the syndrome. The regulatory T cells (Tregs) …

A case for targeting Th17 cells and IL-17A in SARS-CoV-2 infections

M Orlov, PL Wander, ED Morrell… - The Journal of …, 2020 - journals.aai.org
Abstract SARS-CoV-2, the virus causing COVID-19, has infected millions and has caused
hundreds of thousands of fatalities. Risk factors for critical illness from SARS-CoV-2 infection …

The role of Th17 cells in viral infections

PS Aghbash, N Hemmat, JS Nahand… - International …, 2021 - Elsevier
The present review provides an overview of recent advances regarding the function of Th17
cells and their produced cytokines in the progression of viral diseases. Viral infections alone …

Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury

GP Fadanni, JB Calixto - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …

Gut-derived immune cells and the gut-lung axis in ARDS

M Ziaka, A Exadaktylos - Critical Care, 2024 - Springer
The gut serves as a vital immunological organ orchestrating immune responses and
influencing distant mucosal sites, notably the respiratory mucosa. It is increasingly …