[HTML][HTML] Polyphenols inhibiting MAPK signalling pathway mediated oxidative stress and inflammation in depression

T Behl, T Rana, GH Alotaibi, M Shamsuzzaman… - Biomedicine & …, 2022 - Elsevier
Depression is one of the most debilitating psychiatric disorders affecting people of all ages
worldwide. Despite significant heterogeneity between studies, increased inflammation and …

Health benefits of resveratrol: Evidence from clinical studies

AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Polyphenols from food and natural products: Neuroprotection and safety

RFM Silva, L Pogačnik - Antioxidants, 2020 - mdpi.com
Polyphenols are naturally occurring micronutrients that are present in many food sources.
Besides being potent antioxidants, these molecules may also possess anti-inflammatory …

Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway

I Hichri, F Barrieu, J Bogs, C Kappel… - Journal of …, 2011 - academic.oup.com
Flavonoids are secondary metabolites involved in several aspects of plant development and
defence. They colour fruits and flowers, favouring seed and pollen dispersal, and contribute …

Reactive oxygen species, aging, and antioxidative nutraceuticals

J Lee, N Koo, DB Min - … reviews in food science and food safety, 2004 - Wiley Online Library
The important roles of reactive oxygen species in diseases related to aging and the
necessity and benefits of antioxidative nutraceuticals in the prevention of diseases and …

Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies

BB Aggarwal, A Bhardwaj, RS Aggarwal… - Anticancer …, 2004 - ar.iiarjournals.org
Resveratrol, trans-3, 5, 4'-trihydroxystilbene, was first isolated in 1940 as a constituent of the
roots of white hellebore (Veratrum grandiflorum O. Loes), but has since been found in …

A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals

Z Li, H Jiang, C Xu, L Gu - Food Hydrocolloids, 2015 - Elsevier
Phenolic phytochemicals have been of particular interests in food and pharmaceutical fields
because they have potential to reduce the incidences of coronary heart disease, diabetes …

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets

C Ramassamy - European journal of pharmacology, 2006 - Elsevier
Aging is the major risk factor for neurodegenerative diseases such as Alzheimer's and
Parkinson's diseases. A large body of evidence indicates that oxidative stress is involved in …

Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet

BT Jeon, EA Jeong, HJ Shin, Y Lee, DH Lee, HJ Kim… - Diabetes, 2012 - Am Diabetes Assoc
Obesity-induced diabetes is associated with chronic inflammation and is considered a risk
factor for neurodegeneration. We tested the hypothesis that an AMP-activated protein kinase …

Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E

AR Neves, JF Queiroz, S Reis - Journal of nanobiotechnology, 2016 - Springer
Background The present study takes advantage of the beneficial effects of resveratrol as a
neuroprotective compound. Resveratrol-loaded solid lipid nanoparticles were functionalized …