[HTML][HTML] A focus on yeast mating: From pheromone signaling to cell-cell fusion

B Sieber, JM Coronas-Serna, SG Martin - Seminars in cell & developmental …, 2023 - Elsevier
Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …

Regulation of G protein–initiated signal transduction in yeast: paradigms and principles

HG Dohlman, J Thorner - Annual review of biochemistry, 2001 - annualreviews.org
▪ Abstract All cells have the capacity to evoke appropriate and measured responses to signal
molecules (such as peptide hormones), environmental changes, and other external stimuli …

Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast

J Mata, J Bähler - Proceedings of the National Academy of …, 2006 - National Acad Sciences
Fission yeast cells belong to one of two specialized cell types, M or P. Specific
environmental conditions trigger sexual differentiation, which leads to an internal program …

Cdc42 explores the cell periphery for mate selection in fission yeast

FO Bendezú, SG Martin - Current biology, 2013 - cell.com
How cells polarize in response to external cues is a fundamental biological problem. For
mating, yeast cells orient growth toward the source of a pheromone gradient produced by …

Except in Every Detail: Comparing and Contrasting G-Protein Signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe

CS Hoffman - Eukaryotic Cell, 2005 - Am Soc Microbiol
When asked to explain the difference between the mechanisms controlling mating type
switching in the budding yeast Saccharomyces cerevisiae and the fission yeast …

Spatial focalization of pheromone/MAPK signaling triggers commitment to cell–cell fusion

O Dudin, L Merlini, SG Martin - Genes & development, 2016 - genesdev.cshlp.org
Cell fusion is universal in eukaryotes for fertilization and development, but what signals this
process is unknown. Here, we show in Schizosaccharomyces pombe that fusion does not …

Signaling systems of lower eukaryotes and their evolution

AO Shpakov, MN Pertseva - International Review of Cell and Molecular …, 2008 - Elsevier
Making progress in the study of hormone‐sensitive signaling systems in vertebrates and
human requires a better understanding of how chemosignaling systems in lower eukaryotes …

Inhibition of Ras activity coordinates cell fusion with cell–cell contact during yeast mating

L Merlini, B Khalili, O Dudin, L Michon… - Journal of Cell …, 2018 - rupress.org
In the fission yeast Schizosaccharomyces pombe, pheromone signaling engages a
signaling pathway composed of a G protein–coupled receptor, Ras, and a mitogen-activated …

Modified yeast cells to investigate the coupling of G protein‐coupled receptors to specific G proteins

G Ladds, K Davis, EW Hillhouse… - Molecular …, 2003 - Wiley Online Library
G protein‐coupled receptors (GPCRs) help to regulate the physiology of all the major organ
systems. They respond to a multitude of ligands and activate a range of effector proteins to …

RGS proteins: lessons from the RGS9 subfamily

CW Cowan, W He, TG Wensel - 2000 - Elsevier
RGS proteins enhance the time resolution of G protein signaling cascades by accelerating
GTP hydrolysis of Gα subunits of heterotrimeric G proteins. RGS9-1, a photoreceptor-specific …