Hydrogel-based scaffolds to support intrathecal stem cell transplantation as a gateway to the spinal cord: clinical needs, biomaterials, and imaging technologies
The prospects for cell replacement in spinal cord diseases are impeded by inefficient stem
cell delivery. The deep location of the spinal cord and complex surgical access, as well as …
cell delivery. The deep location of the spinal cord and complex surgical access, as well as …
The Polyanalgesic Consensus Conference (PACC)®: Intrathecal drug delivery guidance on safety and therapy optimization when treating chronic noncancer pain
TR Deer, SM Hayek, JS Grider, JM Hagedorn… - … : Technology at the …, 2024 - Elsevier
Abstract Introduction The International Neuromodulation Society convened a multispecialty
group of physicians and scientists based on expertise with international representation to …
group of physicians and scientists based on expertise with international representation to …
Intrathecal therapeutics: device design, access methods, and complication mitigation
Introduction The intrathecal space remains underutilized for diagnostic testing, invasive
monitoring or as a pipeline for the delivery of neurological therapeutic agents and devices …
monitoring or as a pipeline for the delivery of neurological therapeutic agents and devices …
Standardized method for intra-cisterna magna delivery under fluoroscopic guidance in nonhuman primates
N Katz, T Goode, C Hinderer, J Hordeaux… - Human Gene Therapy …, 2018 - liebertpub.com
Intrathecal delivery of adeno-associated virus vectors and other therapeutics are currently
being evaluated for the treatment of central nervous system sequelae of lysosomal storage …
being evaluated for the treatment of central nervous system sequelae of lysosomal storage …
Nusinersen for patients with spinal muscular atrophy: 1415 doses via an interdisciplinary institutional approach
E Madan, S Carrié, C Donado, K Lobo, M Souris… - Pediatric Neurology, 2022 - Elsevier
Background Spinal deformity and prior spinal fusion pose technical challenges to lumbar
puncture (LP) for nusinersen administration for patients with spinal muscular atrophy (SMA) …
puncture (LP) for nusinersen administration for patients with spinal muscular atrophy (SMA) …
Intrathecal pain therapy for the management of chronic noncancer pain
VV Sukul - Neurosurgery Clinics, 2019 - neurosurgery.theclinics.com
Intrathecal pain therapies first began to emerge in the late 1970s with the World Health
Organization's call for a focus on the management of chronic malignant cancer pain. Interest …
Organization's call for a focus on the management of chronic malignant cancer pain. Interest …
Transforaminal lumbar puncture for spinal anesthesia or novel drug administration: a technique combining C-arm fluoroscopy and ultrasound
C Berde, A Formanek, A Khan, CR Camelo… - Regional Anesthesia & …, 2022 - rapm.bmj.com
Background Lumbar puncture (LP) may be challenging for patients with scoliosis and other
conditions following previous posterior fusion and instrumentation from thoracic to sacral …
conditions following previous posterior fusion and instrumentation from thoracic to sacral …
Fluoroscopic-guided paramedian approach for lumbar catheter placement in cerebrospinal fluid shunting: assessment of safety and accuracy
A Tucker, Y Kajimoto, T Ohmura, N Ikeda… - Operative …, 2019 - journals.lww.com
BACKGROUND Spinal catheter insertion in lumboperitoneal (LP) shunt surgery for
idiopathic normal pressure hydrocephalus (iNPH) is frequently associated with technical …
idiopathic normal pressure hydrocephalus (iNPH) is frequently associated with technical …
Intrathecal catheter and port placement for nusinersen infusion in children with spinal muscular atrophy and spinal fusion
Background Spinal administration of medications is challenging in patients with complete
posterior spinal fusion. We describe percutaneous image-guided intrathecal port placement …
posterior spinal fusion. We describe percutaneous image-guided intrathecal port placement …
Neurosurgical management of spastic conditions of the upper extremity
Spasticity is best described as an uninhibited velocity-dependent activation of skeletal
muscle reflexes resulting from upper motor neuron injury. 1, 2 Surgical intervention for …
muscle reflexes resulting from upper motor neuron injury. 1, 2 Surgical intervention for …