Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that
results from mutations in the NF2 tumour suppressor gene located on chromosome 22q. It …

Neurofibromatosis type II (NF2) is a tumor predisposition syndrome characterized by the
development of distinctive nervous system lesions. NF2 results from loss-of-function …

Summary Historically, neurofibromatosis 1 (NF1) has been inextricably linked with
neurofibromatosis 2 (NF2). Both are inherited autosomal-dominant neurocutaneous …

BACKGROUND: We present a series of 179 spinal neurinomas consecutively observed at
the Department of Neurosurgery at the University of Florence for a period of 30 years …

The differential diagnosis of intradural spinal tumors is primarily based on location, but the
clinical presentation, age, and gender of the patient are also important factors in determining …

Background Neurofibromatosis of types 1 and 2 (NF1, NF2) and schwannomatosis are the
diseases that make up the neurofibromatosis spectrum. With respective incidences of 1 in …

Schwannomatosis is characterized by the predisposition to develop multiple schwannomas
and, less commonly, meningiomas. Despite the clinical overlap with neurofibromatosis type …

A consensus conference on neurofibromatosis 2 (NF2) was held in 2002 at the request of
the United Kingdom (UK) Neurofibromatosis Association, with particular emphasis on …

To evaluate clinical and molecular predictors of the risk of mortality in people with
neurofibromatosis 2 (NF2), we analyzed the mortality experience of 368 patients from 261 …

This single-institution phase II study was performed to estimate the response rate to lapatinib
in neurofibromatosis type 2 (NF2) patients with progressive vestibular schwannoma (VS) …