The tight junction (TJ) is an essential component of the differentiated epithelial cell required
for polarised transport and intercellular integrity and signalling. Whilst much can be learnt …

Tight junction formation during development is critical for embryonic patterning and
organization. We consider mechanisms of junction biogenesis in cleaving mouse and …

The cell–cell adhesion molecule N-cadherin strongly promotes neurite outgrowth in cultured
retinal neurons. To test whether cadherins regulate process outgrowth in retinal neurons in …

Convergent extension movements are the main driving force of Xenopus gastrulation. A fine-
tuned regulation of cadherin-mediated cell–cell adhesion is thought to be required for this …

The adhesive function of classical cadherins depends on the association with cytoplasmic
proteins, termed catenins, which serve as a link between cadherins and the actin …

As the first detailed overview of the subject, Tight Junctions brought together diverse
perspectives from leading investigators to provide a multidisciplinary overview of the field …

During Xenopus gastrulation, the internalizing mesendodermal cell mass is brought into
contact with the multilayered blastocoel roof. The two tissues do not fuse, but remain …

The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population,
which migrates directionally on defined routes throughout the embryo, contributing to facial …

Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent
extension during Xenopus laevis gastrulation. These shape changes associated with lateral …

Tight junctions (TJs) perform a critical role in the transport functions and morphogenetic
activity of the primary epithelium formed during Xenopus cleavage. Biogenesis of these …