In recent years, interest in the impact of environmental pollutants on the ecosystem has
increased significantly, with particular attention being paid to the relationship between …

Simple Summary Xenopus laevis is an anuran amphibian that has been used for decades
as the principal vertebrate model to study embryonic development. Among the advantages …

Delorazepam, a derivative of diazepam, is a psychotropic drug belonging to the
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …

Psychoactive compounds, and benzodiazepines (BZPs) in particular, represent an important
class of emerging pollutants due to their large (ab) use and high resistance to degradation …

Traditional teratological protocols in mammals are mandatory for pharmaceutical and
chemical product registration, but require hundreds of animals and are complex and …

Benzodiazepines, psychotropic drugs, are among the most frequently found
pharmaceuticals in aquatic matrices. An increasing number of studies are reporting their …

Emerging contaminants can act as contributing factors to the decline of amphibian
populations worldwide. Recently, scientists have drawn attention to the potential ecotoxicity …

Chemical pollution is a major driver for the current worldwide crisis of amphibian decline.
The present study aimed to assess the influence of polystyrene nanoplastics (PS-NPLs) on …

Freshwater systems are facing a number of pressures due to the inputs of polar organic
contaminants from a range of sources including agriculture, domestic and industry. The …

The frog embryo teratogenesis assay-Xenopus (FETAX) is a standardized test used to
assess the toxic and teratogenic effects of xenobiotics. With this test, toxic and/or teratogenic …