Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

HIV-1 Nef and the unrelated mouse leukaemia virus glycosylated Gag (glycoGag) strongly
enhance the infectivity of HIV-1 virions produced in certain cell types in a clathrin-dependent …

HIV-1 Nef, a protein important for the development of AIDS, has well-characterized effects on
host membrane trafficking and receptor downregulation. By an unidentified mechanism, Nef …

Increasing evidence suggests that durable drug-free control of HIV-1 replication is enabled
by effective cellular immune responses that may induce an attenuated viral reservoir …

Retroviral vectors derived from lentiviruses such as HIV-1 are promising tools for human
gene therapy because they mediate the in vivo delivery and long-term expression of …

A unique cohort of HIV-1-infected long term nonprogressors (LTNP) with normal CD4+ T cell
counts and< 50 copies/ml of plasma were prospectively recruited for study. HLA typing …

Acute human immunodeficiency virus type 1 (HIV-1) infection is a transient symptomatic
illness associated with high-titer HIV-1 replication and a robust and expansive immunologic …

Chronic viral infections can appear in two very different forms: those that are typically
immunologically contained after acute symptomatic infection, such as Epstein-Barr virus …

The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …