Phage puppet masters of the marine microbial realm

M Breitbart, C Bonnain, K Malki, NA Sawaya - Nature microbiology, 2018 - nature.com
Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …

Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

S Roux, JR Brum, BE Dutilh, S Sunagawa… - Nature, 2016 - nature.com
Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

Patterns and ecological drivers of ocean viral communities

JR Brum, JC Ignacio-Espinoza, S Roux, G Doulcier… - Science, 2015 - science.org
Viruses influence ecosystems by modulating microbial population size, diversity, metabolic
outputs, and gene flow. Here, we use quantitative double-stranded DNA (dsDNA) viral …

Prochlorococcus: the structure and function of collective diversity

SJ Biller, PM Berube, D Lindell… - Nature Reviews …, 2015 - nature.com
The marine cyanobacterium Prochlorococcus is the smallest and most abundant
photosynthetic organism on Earth. In this Review, we summarize our understanding of the …

Phages in nature

MRJ Clokie, AD Millard, AV Letarov, S Heaphy - Bacteriophage, 2011 - Taylor & Francis
Phages are the most abundant organisms in the biosphere and they are a ubiquitous feature
of prokaryotic existence. A bacteriophage is a virus which infects a bacterium. Archaea are …

Bacterial vesicles in marine ecosystems

SJ Biller, F Schubotz, SE Roggensack, AW Thompson… - science, 2014 - science.org
Many heterotrophic bacteria are known to release extracellular vesicles, facilitating
interactions between cells and their environment from a distance. Vesicle production has not …

Rising to the challenge: accelerated pace of discovery transforms marine virology

JR Brum, MB Sullivan - Nature Reviews Microbiology, 2015 - nature.com
Marine viruses have important roles in microbial mortality, gene transfer, metabolic
reprogramming and biogeochemical cycling. In this Review, we discuss recent technological …

Phamerator: a bioinformatic tool for comparative bacteriophage genomics

SG Cresawn, M Bogel, N Day, D Jacobs-Sera… - BMC …, 2011 - Springer
Background Bacteriophage genomes have mosaic architectures and are replete with small
open reading frames of unknown function, presenting challenges in their annotation …

Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism

LR Thompson, Q Zeng, L Kelly… - Proceedings of the …, 2011 - National Acad Sciences
Cyanophages infecting the marine cyanobacteria Prochlorococcus and Synechococcus
encode and express genes for the photosynthetic light reactions. Sequenced cyanophage …