Harnessing amphiphilic polymeric micelles for diagnostic and therapeutic applications: Breakthroughs and bottlenecks

J Kaur, V Mishra, SK Singh, M Gulati, B Kapoor… - Journal of Controlled …, 2021 - Elsevier
Amphiphilic block copolymers are widely utilized in the design of formulations owing to their
unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic …

Hydrogels with smart systems for delivery of hydrophobic drugs

D Gu, AJ O'Connor, G GH Qiao… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Smart hydrogel systems present opportunities to not only provide hydrophobic
molecule encapsulation capability but to also respond to specific delivery routes. Areas …

pH-sensitive micelles self-assembled from multi-arm star triblock co-polymers poly (ε-caprolactone)-b-poly (2-(diethylamino) ethyl methacrylate)-b-poly (poly (ethylene …

YQ Yang, B Zhao, ZD Li, WJ Lin, CY Zhang, XD Guo… - Acta biomaterialia, 2013 - Elsevier
A series of amphiphilic 4-and 6-armed star triblock co-polymers poly (ε-caprolactone)-b-poly
(2-(diethylamino) ethyl methacrylate)-b-poly (poly (ethylene glycol) methyl ether …

Amphiphilic miktoarm star copolymer (PCL) 3-(PDEAEMA-b-PPEGMA) 3 as pH-sensitive micelles in the delivery of anticancer drug

W Lin, S Nie, Q Zhong, Y Yang, C Cai… - Journal of Materials …, 2014 - pubs.rsc.org
Well-defined A3 (BC) 3 type amphiphilic miktoarm star polymers poly (ε-caprolactone) 3-
[poly (2-(diethylamino) ethyl methacrylate)-b-poly (poly (ethylene glycol) methyl ether …

Efficient multiblock star polymer synthesis from photo-induced copper-mediated polymerization with up to 21 arms

B Wenn, AC Martens, YM Chuang, J Gruber… - Polymer …, 2016 - pubs.rsc.org
Photo-induced copper-mediated polymerization (photoCMP) is employed for the synthesis
of multiarm-multiblock star copolymers. Based on a core-first approach, star polymers with …

Complex polymeric architectures self-assembling in unimolecular micelles: preparation, characterization and drug nanoencapsulation

S Ordanini, F Cellesi - Pharmaceutics, 2018 - mdpi.com
Unimolecular polymeric micelles are a class of single-molecule amphiphilic core-shell
polymeric architectures, where the hydrophobic core is well stabilized by the hydrophilic …

Multi-walled carbon nanotubes-g-[poly(ethylene glycol)-b-poly(ε-caprolactone)]: synthesis, characterization, and properties

B Massoumi, M Ramezani, M Jaymand… - Journal of Polymer …, 2015 - Springer
This paper describes the synthesis, characterization, and material properties of multi-walled
carbon nanotubes-g-[poly (ethylene glycol)-b-poly (ε-caprolactone)](MWCNTs-g-(PEG-b …

Amphiphilic thermoresponsive copolymer bottlebrushes: Synthesis, characterization, and study of their self-assembly into flower-like micelles

AР Sivokhin, DV Orekhov, OA Kazantsev… - Polymer Journal, 2021 - nature.com
Amphiphilic thermoresponsive copolymer bottlebrushes based on methoxy oligo (ethylene
glycol) 7 methacrylate and alkoxy (C12–C14) oligo (ethylene glycol) 6 methacrylate have …

Thermo-responsive “hairy-rod” polypeptides for smart antitumor drug delivery

J Ding, L Zhao, D Li, C Xiao, X Zhuang, X Chen - Polymer Chemistry, 2013 - pubs.rsc.org
A series of thermo-responsive “hairy-rod” polypeptides was efficiently synthesized by
grafting of azide-terminated (co) polymers of 2-(2-methoxyethoxy) ethyl methacrylate …

Microparticles-in-thermoresponsive/bioadhesive hydrogels as a novel integrated platform for effective intra-articular delivery of triamcinolone acetonide

M Abou-ElNour, ME Soliman, A Skouras… - Molecular …, 2020 - ACS Publications
Intra-articular (IA) injection of thermoresponsive hydrogels coupled with microparticles (MPs)
possess the benefit of sustaining the anti-inflammatory drug effect within the joint cavity for …