Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …

Cancer is one of the most frequently diagnosed diseases, and despite the continuous efforts
in searching for new and more effective treatments, its morbidity and mortality remain a …

Background/aim Autophagy is a macromolecular degradation process playing a pivotal role
in the maintenance of stem-like features and in the morpho-functional remodeling of the …

Alterations in autophagy and the ubiquitin proteasome system (UPS) are commonly
implicated in protein aggregation and toxicity which manifest in a number of neurological …

Marine benthic invertebrates are frequently exposed to fluctuating oxygen levels resulting in
hypoxia-reoxygenation (H/R) stress in the intertidal, estuarine and shallow coastal habitats …

In recent years considerable progress has been made in identifying the impact of mRNA
translation in tumour progression. Cancer cells hijack the pre-existing translation machinery …

Ovarian cancer (OC) is characterized by a high mortality rate due to the late diagnosis and
the elevated metastatic potential. Autophagy, a lysosomal-driven catabolic process …

As a major eukaryotic cell clearing machinery, autophagy grants cell proteostasis, which is
key for neurotransmitter release, synaptic plasticity, and neuronal survival. In line with this …

Background Electroacupuncture (EA), a treatment derived from traditional Chinese
medicine, can effectively improve hyperandrogenism and insulin resistance in patients with …

Keloids are characterized by increased deposition of fibrous tissue in the skin and
subcutaneous tissue following an abnormal wound healing process. Although keloid …