The cardiac autonomic nervous system (ANS) plays an integral role in normal cardiac
physiology as well as in disease states that cause cardiac arrhythmias. The cardiac ANS …

The autonomic nervous system plays a central role in the pathogenesis of multiple cardiac
arrhythmias, including atrial fibrillation and ventricular tachycardia. As such, autonomic …

Autonomic neuromodulation therapies (ANMTs)(ie, ganglionated plexus ablation, epicardial
injections for temporary neurotoxicity, low-level vagus nerve stimulation [LL-VNS], stellate …

Many cardiac electrophysiological abnormalities are accompanied by autonomic nervous
system dysfunction. Here, we review mechanisms by which the cardiac nervous system …

Background Previous study has shown that spinal cord stimulation (SCS) may suppress
atrial fibrillation (AF) inducibility, but the mechanism for this is elusive. Objective The …

Vagus nerve stimulation improves left ventricular (LV) remodeling by downregulation of
matrix metalloproteinase 9 (MMP-9) and transforming growth factor β1 (TGF-β1). Our …

The autonomic nervous system (ANS) plays a critical role in both health and states of
cardiovascular disease. There has been a long-recognized role of the ANS in the …

Background: The NRG1/ErbB4 signaling mechanism has been widely studied in the central
nervous system for many years. However, the role of this pathway in modulating the intrinsic …

Abstract Purpose of Review Neuromodulation for the management of atrial fibrillation (AF)
has been a topic of increased interest in recent years; however, there are still challenges …

Objective To investigate the effect of the mutual regulation of the extrinsic cardiac nerves on
atrial electrophysiology and atrial fibrillation (AF) vulnerability. Methods and results Fourteen …