Adiponectin regulation and function

H Fang, RL Judd - Comprehensive Physiology, 2011 - Wiley Online Library
Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Maternal and fetal lipid metabolism under normal and gestational diabetic conditions

E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …

[PDF][PDF] Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes.

LA Barbour, CE McCurdy, TL Hernandez… - Diabetes …, 2007 - researchgate.net
The incidence of gestational diabetes mellitus (GDM) has doubled over the last 6–8 years
and is paralleling the obesity epidemic. GDM carries longterm implications for the …

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

J Ye, Z Gao, J Yin, Q He - American Journal of Physiology …, 2007 - journals.physiology.org
Chronic inflammation and reduced adiponectin are widely observed in the white adipose
tissue in obesity. However, the cause of the changes remains to be identified. In this study …

Adiponectin: regulation of its production and its role in human diseases

A Shehzad, W Iqbal, O Shehzad, YS Lee - Hormones, 2012 - Springer
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding
protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1 …

Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading

MS Madsen, R Siersbæk, M Boergesen… - … and cellular biology, 2014 - Am Soc Microbiol
Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein
α (C/EBPα) are key activators of adipogenesis. They mutually induce the expression of each …

Mechanisms of chronic state of inflammation as mediators that link obese adipose tissue and metabolic syndrome

E Fuentes, F Fuentes, G Vilahur… - Mediators of …, 2013 - Wiley Online Library
The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence
of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is …

SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein α transcriptional complex

L Qiao, J Shao - Journal of Biological Chemistry, 2006 - ASBMB
Adiponectin is an adipose-derived hormone that plays an important role in maintaining
energy homeostasis. Adiponectin gene expression is diminished in both obesity and type 2 …

Mechanisms of adiponectin action in fertility: an overview from gametogenesis to gestation in humans and animal models in normal and pathological conditions

A Barbe, A Bongrani, N Mellouk, A Estienne… - International journal of …, 2019 - mdpi.com
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose
tissue and plays a key role in the control of energy metabolism thanks to its insulin …

Transcriptional and post-translational regulation of adiponectin

M Liu, F Liu - Biochemical Journal, 2010 - portlandpress.com
Adiponectin is an adipose-tissue-derived hormone with anti-diabetic, anti-atherogenic and
anti-inflammatory functions. Adiponectin circulates in the bloodstream in trimeric, hexameric …