Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications
S Zheng, X Wang, D Zhao, H Liu, Y Hu - Trends in Cell Biology, 2023 - cell.com
Calcium ion (Ca 2+) is a ubiquitous and versatile signaling molecule controlling a wide
variety of cellular processes, such as proliferation, cell death, migration, and immune …
variety of cellular processes, such as proliferation, cell death, migration, and immune …
Therapeutic potential of natural products in treating neurodegenerative disorders and their future prospects and challenges
Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …
extensively studied in recent years for their therapeutic potential in a variety of …
Recent advances in calcium‐based anticancer nanomaterials exploiting calcium overload to trigger cell apoptosis
Calcium ion is vital for the regulation of many cellular functions and serves as a second
messenger in the signal transduction pathways. Once the intracellular Ca2+ level exceeds …
messenger in the signal transduction pathways. Once the intracellular Ca2+ level exceeds …
Mitochondria associated membranes (MAMs): architecture and physiopathological role
L Barazzuol, F Giamogante, T Calì - Cell calcium, 2021 - Elsevier
In the last decades, the communication between the Endoplasmic reticulum (ER) and
mitochondria has obtained great attention: mitochondria-associated membranes (MAMs) …
mitochondria has obtained great attention: mitochondria-associated membranes (MAMs) …
ER-mitochondria contact sites; a multifaceted factory for Ca2+ signaling and lipid transport
ML Sassano, B Felipe-Abrio… - Frontiers in Cell and …, 2022 - frontiersin.org
Membrane contact sites (MCS) between organelles of eukaryotic cells provide structural
integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange …
integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange …
Balancing energy and protein homeostasis at ER-mitochondria contact sites
The endoplasmic reticulum (ER) is the largest organelle of the cell and participates in
multiple essential functions, including the production of secretory proteins, lipid synthesis …
multiple essential functions, including the production of secretory proteins, lipid synthesis …
Balancing ER-mitochondrial Ca2+ fluxes in health and disease
J Loncke, A Kaasik, I Bezprozvanny, JB Parys… - Trends in cell …, 2021 - cell.com
Organelles cooperate with each other to control cellular homeostasis and cell functions by
forming close connections through membrane contact sites. Important contacts are present …
forming close connections through membrane contact sites. Important contacts are present …
Ca2+ signaling and cell death
Multiple forms of regulated cell death (RCD) have been characterized, each of which
originates from the activation of a dedicated molecular machinery. RCD can occur in purely …
originates from the activation of a dedicated molecular machinery. RCD can occur in purely …
The two-way relationship between calcium and metabolism in cancer
C Dejos, D Gkika, AR Cantelmo - Frontiers in Cell and …, 2020 - frontiersin.org
Calcium ion (Ca2+) signaling is critical to many physiological processes, and its kinetics and
subcellular localization are tightly regulated in all cell types. All Ca2+ flux perturbations …
subcellular localization are tightly regulated in all cell types. All Ca2+ flux perturbations …
Extracellular matrix signals as drivers of mitochondrial bioenergetics and metabolic plasticity of cancer cells during metastasis
FA Urra, S Fuentes-Retamal, C Palominos… - Frontiers in cell and …, 2021 - frontiersin.org
The role of metabolism in tumor growth and chemoresistance has received considerable
attention, however, the contribution of mitochondrial bioenergetics in migration, invasion …
attention, however, the contribution of mitochondrial bioenergetics in migration, invasion …