Photoactive ruthenium nitrosyls as NO donors: how to sensitize them toward visible light
NL Fry, PK Mascharak - Accounts of chemical research, 2011 - ACS Publications
Nitric oxide (NO) can induce apoptosis (programmed cell death) at micromolar or higher
doses. Although cell death via NO-induced apoptosis has been studied quite extensively …
doses. Although cell death via NO-induced apoptosis has been studied quite extensively …
Photoactive ruthenium nitrosyls: Effects of light and potential application as NO donors
MJ Rose, PK Mascharak - Coordination chemistry reviews, 2008 - Elsevier
In recent years, various exogenous nitric oxide (NO) donors have been synthesized to
modulate NO concentrations in cellular environments and control physiological processes …
modulate NO concentrations in cellular environments and control physiological processes …
Biological activity of ruthenium nitrosyl complexes
Nitric oxide plays an important role in various biological processes, such as
neurotransmission, blood pressure control, immunological responses, and antioxidant …
neurotransmission, blood pressure control, immunological responses, and antioxidant …
Sensitization of ruthenium nitrosyls to visible light via direct coordination of the dye resorufin: trackable NO donors for light-triggered NO delivery to cellular targets
MJ Rose, NL Fry, R Marlow, L Hinck… - Journal of the …, 2008 - ACS Publications
Three nitrosyl-dye conjugates, namely,[(Me2bpb) Ru (NO)(Resf)](1-Resf),[(Me2bQb) Ru
(NO)(Resf)](2-Resf), and [((OMe) 2bQb) Ru (NO)(Resf)](3-Resf) have been synthesized via …
(NO)(Resf)](2-Resf), and [((OMe) 2bQb) Ru (NO)(Resf)](3-Resf) have been synthesized via …
Fiat Lux: selective delivery of high flux of nitric oxide (NO) to biological targets using photoactive metal nitrosyls
MJ Rose, PK Mascharak - Current Opinion in Chemical Biology, 2008 - Elsevier
In addition to its beneficial roles in blood pressure regulation, immune response,
neurotransmission, and redox balance, nitric oxide (NO) can induce cellular apoptosis at …
neurotransmission, and redox balance, nitric oxide (NO) can induce cellular apoptosis at …
Synthesis, DNA-binding and photocleavage studies of ruthenium complexes [Ru (bpy) 2 (mitatp)] 2+ and [Ru (bpy) 2 (nitatp)] 2+
HJ Yu, SM Huang, LY Li, HN Jia, H Chao… - Journal of inorganic …, 2009 - Elsevier
Two new ruthenium complexes [Ru (bpy) 2 (mitatp)](ClO4) 21 and [Ru (bpy) 2 (nitatp)](ClO4)
22 (bpy= 2, 2′-bipyridine, mitatp= 5-methoxy-isatino [1, 2-b]-1, 4, 8, 9-tetraazatriphenylene …
22 (bpy= 2, 2′-bipyridine, mitatp= 5-methoxy-isatino [1, 2-b]-1, 4, 8, 9-tetraazatriphenylene …
Recent advances on the development of NO-releasing molecules (NORMs) for biomedical applications
Nitric oxide (NO) is an important biological messenger as well as a signaling molecule that
participates in a broad range of physiological events and therapeutic applications in …
participates in a broad range of physiological events and therapeutic applications in …
Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities
GL Sasahara, FSG Júnior… - Journal of Inorganic …, 2020 - Elsevier
Inflammation is a physiological process triggered in response to tissue damage, and
involves events related to cell recruitment, cytokines release and reactive oxygen species …
involves events related to cell recruitment, cytokines release and reactive oxygen species …
Influence of ancillary ligand L in the nitric oxide photorelease by the [Ru (L)(tpy) NO] 3+ complex and its vasodilator activity based on visible light irradiation
RG de Lima, MG Sauaia, D Bonaventura… - Inorganica chimica …, 2006 - Elsevier
The photochemical and pharmacological studies of the novel [Ru (L)(tpy) NO] 3+ L= bpy (2,
2′-bipyridine), NH· NHq (quinonediimine) and NH2. NH2cat (o-phenylenediamine) were …
2′-bipyridine), NH· NHq (quinonediimine) and NH2. NH2cat (o-phenylenediamine) were …
Photosensitization of Ruthenium nitrosyls to red light with an isoelectronic series of heavy-atom chromophores: experimental and density functional theory studies on …
MJ Rose, PK Mascharak - Inorganic chemistry, 2009 - ACS Publications
Three ruthenium nitrosyl-dye conjugates, namely,[((OMe) 2bQb) Ru (NO)(Resf)](RuNO-
Resf),[((OMe) 2bQb) Ru (NO)(Thnl)](RuNO-Thnl), and [((OMe) 2bQb) Ru (NO)(Seln)](RuNO …
Resf),[((OMe) 2bQb) Ru (NO)(Thnl)](RuNO-Thnl), and [((OMe) 2bQb) Ru (NO)(Seln)](RuNO …