The prospect of transplanting cells and tissues without the risk of immune rejection or the
need for powerful immunosuppressive drugs is the 'holy grail'of transplantation medicine …

Stem cells represent natural units of embryonic development and tissue regeneration.
Embryonic stem (ES) cells, in particular, possess a nearly unlimited self-renewal capacity …

Suppose a school were to set out deliberately to improve the mental and physical capacities
of its students. Suppose its stated aims were to ensure that the pupils left the school not only …

Mammalian development commences with the totipotent zygote which is capable of
developing into all the specialized cells that make up the adult animal. As development …

Somatic cell nuclear transfer (SCNT) technology has recently been used to generate
animals with a common genetic composition. In this study, we report the derivation of a …

The strictly maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) in
mammals is a developmental paradox promoted by an unknown mechanism responsible for …

This review discusses current understanding of the role that endogenous and exogenous
progenitor cells may have in the treatment of the diseased heart. In the last several years, a …

Cell microencapsulation continues to hold significant promise for biotechnology and
medicine. The controlled, and continuous, delivery of therapeutic products to the host by …

Approximately 100 species become extinct a day. Despite increasing interest in using
cloning to rescue endangered species, successful interspecies nuclear transfer has not …

The potential of cloning depends in part on whether the procedure can reverse cellular
aging and restore somatic cells to a phenotypically youthful state. Here, we report the birth of …