Updated clinical perspectives and challenges of chimeric antigen receptor-T cell therapy in colorectal cancer and invasive breast cancer
Y Cao, SK Efetov, M He, Y Fu, NM Beeraka… - Archivum Immunologiae …, 2023 - Springer
In recent years, the incidence of colorectal cancer (CRC) and breast cancer (BC) has
increased worldwide and caused a higher mortality rate due to the lack of selective anti …
increased worldwide and caused a higher mortality rate due to the lack of selective anti …
Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull's eye for targeted therapy?
X Chen, SJ Keller, P Hafner, AY Alrawashdeh… - Frontiers in …, 2024 - frontiersin.org
Encoded by PTPN11, the Src-homology 2 domain-containing phosphatase 2 (SHP2)
integrates signals from various membrane-bound receptors such as receptor tyrosine …
integrates signals from various membrane-bound receptors such as receptor tyrosine …
FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
W Wei, B Qin, W Wen, B Zhang, H Luo… - … and Targeted Therapy, 2023 - nature.com
Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor.
FBXW7 is a highly mutated gene in CRC, but its biological functions in cancer are not fully …
FBXW7 is a highly mutated gene in CRC, but its biological functions in cancer are not fully …
Overcoming Resistance to Standard-of-Care Therapies for Head and Neck Squamous Cell Carcinomas
C Gauss, LD Stone, M Ghafouri, D Quan, J Johnson… - Cells, 2024 - mdpi.com
Although there have been some advances during in recent decades, the treatment of head
and neck squamous cell carcinoma (HNSCC) remains challenging. Resistance is a major …
and neck squamous cell carcinoma (HNSCC) remains challenging. Resistance is a major …
Patients with Systemic Juvenile Idiopathic Arthritis (SJIA) Show Differences in Autoantibody Signatures Based on Disease Activity
J Krainer, M Hendling, S Siebenhandl, S Fuehner… - Biomolecules, 2023 - mdpi.com
Systemic juvenile idiopathic arthritis (SJIA) is a severe rheumatic disease in children. It is a
subgroup of juvenile idiopathic arthritis (JIA; MIM# 604302), which is the most common …
subgroup of juvenile idiopathic arthritis (JIA; MIM# 604302), which is the most common …
EFR3A: a new raft domain organizing protein?
M Trybus, A Hryniewicz-Jankowska… - Cellular & Molecular …, 2023 - Springer
Background Membrane rafts play a crucial role in the regulation of many important biological
processes. Our previous data suggest that specific interactions of flotillins with MPP1 are …
processes. Our previous data suggest that specific interactions of flotillins with MPP1 are …