The action potential of the squid giant axon is formed by just two voltage-dependent
conductances in the cell membrane, yet mammalian central neurons typically express more …

As indicated by the profound cognitive impairments caused by cholinergic receptor
antagonists, cholinergic neurotransmission has a vital role in cognitive function, specifically …

Glucose is the mandatory fuel for the brain, yet the relative contribution of glucose and
lactate for neuronal energy metabolism is unclear. We found that increased lactate, but not …

The transient receptor potential (TRP) protein superfamily consists of a diverse group of
cation channels that bear structural similarities to Drosophila TRP. TRP channels play …

The TRPM subfamily of mammalian TRP channels displays unusually diverse activation
mechanisms and selectivities [1]. One member of this subfamily, TRPM5, functions in taste …

A limited number (7±2) of items can be held in human short-term memory (STM). We have
previously suggested that observed dual (theta and gamma) oscillations could underlie a …

The input–output relationship of neuronal networks depends both on their synaptic
connectivity and on the intrinsic properties of their neuronal elements. In addition to altered …

Neuropeptide Y (NPY) is an abundant neuropeptide of the neocortex involved in numerous
physiological and pathological processes. Because of the large electrophysiological …

Mammals can reliably predict the time of occurrence of an expected event after a predictive
stimulus. Climbing activity is a prominent profile of neural activity observed in prefrontal …

1 Chronically epileptic rats, produced by prior injection of pilocarpine, were used to
investigate whether changes in intrinsic neuronal excitability may contribute to the …