[HTML][HTML] Consensus guidelines for implementing pencil-beam scanning proton therapy for thoracic malignancies on behalf of the PTCOG thoracic and lymphoma …

JY Chang, X Zhang, A Knopf, H Li, S Mori… - International Journal of …, 2017 - Elsevier
Pencil-beam scanning (PBS) proton therapy (PT), particularly intensity modulated PT,
represents the latest advanced PT technology for treating cancers, including thoracic …

[HTML][HTML] Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

Exploratory study of 4D versus 3D robust optimization in intensity modulated proton therapy for lung cancer

W Liu, SE Schild, JY Chang, Z Liao, YH Chang… - International Journal of …, 2016 - Elsevier
Purpose The purpose of this study was to compare the impact of uncertainties and interplay
on 3-dimensional (3D) and 4D robustly optimized intensity modulated proton therapy (IMPT) …

Evaluation of motion mitigation using abdominal compression in the clinical implementation of pencil beam scanning proton therapy of liver tumors

L Lin, K Souris, M Kang, A Glick, H Lin… - Medical …, 2017 - Wiley Online Library
Purpose To determine whether individual liver tumor patients can be safely treated with
pencil beam scanning proton therapy. This study reports a planning preparation workflow …

Commissioning and beam characterization of the first gantry‐mounted accelerator pencil beam scanning proton system

M Kang, D Pang - Medical physics, 2020 - Wiley Online Library
Purpose To present and discuss beam characteristics and commissioning process of the first
gantry‐mounted accelerator single room pencil beam scanning (PBS) proton system …

AAPM Task Group Report 290: Respiratory motion management for particle therapy

H Li, L Dong, C Bert, J Chang, S Flampouri… - Medical …, 2022 - Wiley Online Library
Dose uncertainty induced by respiratory motion remains a major concern for treating
thoracic and abdominal lesions using particle beams. This Task Group report reviews the …

[HTML][HTML] Managing treatment-related uncertainties in proton beam radiotherapy for gastrointestinal cancers

EJ Tryggestad, W Liu, MD Pepin… - Journal of …, 2020 - ncbi.nlm.nih.gov
In recent years, there has been rapid adaption of proton beam radiotherapy (RT) for
treatment of various malignancies in the gastrointestinal (GI) tract, with increasing number of …

Limited impact of setup and range uncertainties, breathing motion, and interplay effects in robustly optimized intensity modulated proton therapy for stage III non-small …

T Inoue, J Widder, LV van Dijk, H Takegawa… - International Journal of …, 2016 - Elsevier
Purpose To investigate the impact of setup and range uncertainties, breathing motion, and
interplay effects using scanning pencil beams in robustly optimized intensity modulated …

Impact of spot size and spacing on the quality of robustly optimized intensity modulated proton therapy plans for lung cancer

C Liu, SE Schild, JY Chang, Z Liao, S Korte… - International Journal of …, 2018 - Elsevier
Purpose To investigate how spot size and spacing affect plan quality, robustness, and
interplay effects of robustly optimized intensity modulated proton therapy (IMPT) for lung …

Dosimetric comparison of distal esophageal carcinoma plans for patients treated with small‐spot intensity‐modulated proton versus volumetric‐modulated arc …

C Liu, RS Bhangoo, TT Sio, NY Yu… - Journal of applied …, 2019 - Wiley Online Library
Background Esophageal carcinoma is the eighth most common cancer in the world.
Volumetric‐modulated arc therapy (VMAT) is widely used to treat distal esophageal …