The red flour beetle T. castaneum: elaborate genetic toolkit and unbiased large scale RNAi screening to study insect biology and evolution

M Klingler, G Bucher - EvoDevo, 2022 - Springer
The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

Changes in both trans- and cis-regulatory elements mediate insecticide resistance in a lepidopteron pest, Spodoptera exigua

B Hu, H Huang, S Hu, M Ren, Q Wei, X Tian… - PLoS …, 2021 - journals.plos.org
The evolution of insect resistance to insecticides is frequently associated with
overexpression of one or more cytochrome P450 enzyme genes. Although overexpression …

Enhanced genome assembly and a new official gene set for Tribolium castaneum

N Herndon, J Shelton, L Gerischer, P Ioannidis… - BMC genomics, 2020 - Springer
Background The red flour beetle Tribolium castaneum has emerged as an important model
organism for the study of gene function in development and physiology, for ecological and …

The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology

C Schmitt-Engel, D Schultheis, J Schwirz… - Nature …, 2015 - nature.com
Genetic screens are powerful tools to identify the genes required for a given biological
process. However, for technical reasons, comprehensive screens have been restricted to …

The insect central complex as model for heterochronic brain development—background, concepts, and tools

NDB Koniszewski, M Kollmann, M Bigham… - Development genes and …, 2016 - Springer
The adult insect brain is composed of neuropils present in most taxa. However, the relative
size, shape, and developmental timing differ between species. This diversity of adult insect …

[HTML][HTML] Hedgehog signaling regulates imaginal cell differentiation in a basally branching holometabolous insect

CM Villarreal, K Darakananda, VR Wang… - Developmental …, 2015 - Elsevier
The evolution of imaginal cells, or stem cell-like cells, contributed to the spectacular
diversification of holometabolous insects, which undergo complete metamorphosis. The …

A molecular view of onychophoran segmentation

R Janssen - Arthropod structure & development, 2017 - Elsevier
This paper summarizes our current knowledge on the expression and assumed function of
Drosophila and (other) arthropod segmentation gene orthologs in Onychophora, a closely …

The neuroblast timer gene nubbin exhibits functional redundancy with gap genes to regulate segment identity in Tribolium

ORA Tidswell, MA Benton, M Akam - Development, 2021 - journals.biologists.com
The neuroblast timer genes hunchback, Krüppel, nubbin and castor are expressed in
temporal sequence in neural stem cells, and in corresponding spatial sequence along the …

The function and evolution of nuclear receptors in insect embryonic development

AMC Jarvela, L Pick - Current Topics in Developmental Biology, 2017 - Elsevier
Nuclear receptors are a family of transcription factors that are often responsive to small
ligands, allowing for efficient gene expression-level responses to a stimulus. The average …

Light sheet-based fluorescence microscopy of living or fixed and stained Tribolium castaneum embryos

F Strobl, S Klees, EHK Stelzer - JoVE (Journal of Visualized Experiments), 2017 - jove.com
The red flour beetle Tribolium castaneum has become an important insect model organism
in developmental genetics and evolutionary developmental biology. The observation of …