Glia of the central nervous system (CNS) help to maintain homeostasis in the brain and
support efficient neuronal function. Microglia are innate immune cells of the brain that …

The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …

More Americans are consuming diets higher in saturated fats and refined sugars than ever
before, and based on increasing obesity rates, this is a growing trend among older adults as …

Although morphine remains the primary drug prescribed for alleviation of severe or
persistent pain, both preclinical and clinical studies have shown that females require two to …

In this study, we tested our hypothesis regarding mechanistic cross-talk between
gastrointestinal inflammation and memory loss in a mouse model. Intrarectal injection of the …

The blood–CSF barrier (BCSFB) consists of a monolayer of choroid plexus epithelial (CPE)
cells that maintain CNS homeostasis by producing CSF and restricting the passage of …

Purpose Chemotherapy-related cognitive impairment (CRCI) is commonly reported
following the administration of chemotherapeutic agents and comprises a wide variety of …

Numerous studies have reported the importance of microglial activation in various
pathological conditions, whereas little attention has been given to the point for dynamics of …

Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its
potential therapeutic use in the treatment of many diseases, including cancer, diabetes …

Neuropeptide Y (NPY), one of the most abundant peptides in the nervous system, exerts its
effects via five receptor types, termed Y 1, Y 2, Y 4, Y 5 and Y 6. NPY's pleiotropic functions …