Tanshinone IIA targeting cell signaling pathways: A plausible paradigm for cancer therapy

SSM Alam, A Samanta, F Uddin, S Ali… - Pharmacological Reports, 2023 - Springer
Natural compounds originating from plants offer a wide range of pharmacological potential
and have traditionally been used to treat a wide range of diseases including cancer …

Curcumin and plumbagin synergistically target the PI3K/Akt/mTOR pathway: a prospective role in cancer treatment

I Ahmad, M Hoque, SSM Alam, TA Zughaibi… - International journal of …, 2023 - mdpi.com
Cancer development is associated with the deregulation of various cell signaling pathways
brought on by certain genetic and epigenetic alterations. Therefore, novel therapeutic …

[HTML][HTML] Therapeutic and pharmacological potential of Tanshinones against lung cancer: A systematic review

SSM Alam, F Uddin, FB Khan, MA Kamal, M Hoque - Phytomedicine Plus, 2022 - Elsevier
Background Lung cancer is the most prevalent of all cancers, causing the highest number of
cancer-related deaths in men and the second-highest number in women worldwide. Recent …

[Retracted] Identification of Potential Poly (ADP‐Ribose) Polymerase‐1 Inhibitors Derived from Rauwolfia serpentina: Possible Implication in Cancer Therapy

AM Abuzenadah, F Al-Sayes… - Evidence‐Based …, 2022 - Wiley Online Library
Poly (ADP‐ribose) polymerase‐1 (PARP‐1) has been recognized as a prospective target for
the development of novel cancer therapeutics. Several PARP‐1 inhibitors are currently …

[HTML][HTML] Identification of anticancer bioactive compounds derived from Ficus sp. by targeting Poly [ADP-ribose] polymerase 1 (PARP-1)

S Tabrez, M Hoque, M Suhail, MI Khan… - Journal of King Saud …, 2022 - Elsevier
The nuclear enzyme Poly [ADP-ribose] polymerase 1 (PARP-1) facilitates DNA damage
repair which is essential for maintaining genome integrity. The PARP-1 has been touted as …

Nature's Arsenal: Harnessing the Capacity of Phytochemicals to Enhance Immune Checkpoint Inhibitor Therapy of Cancers: An Especial Attention to Brain …

AR Afshari, M Sanati, SS Ahmadi, P Kesharwani… - Cancer Letters, 2024 - Elsevier
Brain cancers, particularly glioblastoma multiforme (GBM), are challenging health issues
with frequent unmet aspects. Today, discovering safe and effective therapeutic modalities for …

Phenolic compounds from Gomphrena globosa L.: phytochemical analysis, antioxidant, antimicrobial, and enzyme inhibitory activities in vitro

SR Tang, YX Sun, TT Gu, FF Cao, YB Shen… - CyTA-Journal of …, 2022 - Taylor & Francis
In the present study, phenolic compounds from Gomphrena globosa L.(GGLPCs) including
total phenols, flavonoids, flavonols, flavanols, and phenolic acids were measured by …

[HTML][HTML] Prospective Pharmacological Potential of Cryptotanshinone in Cancer Therapy

A Ahamed, M Hasan, A Samanta, SSM Alam… - Pharmacological …, 2023 - Elsevier
ABSTRACT Background: Cryptotanshinone (CPT), a Traditional Chinese Medicine (TCM)
has recently gained remarkable interest as a potent alternative cancer therapeutic. The sole …

[PDF][PDF] Phytomedicine Plus

L Adams, M Afiadenyo, SK Kwofie, MD Wilson, KA Kusi… - researchgate.net
Background: Malaria remains a major health concern in developing countries with high
morbidity and mortality, especially in pregnant women and infants. A major obstacle to the …