Parkinson's disease belongs to a group of currently incurable neurodegenerative disorders
characterized by the misfolding and accumulation of alpha‐synuclein aggregates that are …

Over the last two decades, many experimental and clinical studies have provided solid
evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to …

A central hallmark of Alzheimer's disease is the presence of extracellular amyloid plaques
chiefly consisting of amyloid-β (Aβ) peptides in the brain interstitium. Aβ largely exists in two …

The accumulation of α-synuclein (α-syn) aggregates in specific brain regions is a hallmark of
synucleinopathies including Parkinson disease (PD). α-Syn aggregates propagate in a …

Blood-based biomarkers are needed to be used as easy, reproducible, and non-invasive
tools for the diagnosis and prognosis of chronic neurodegenerative disorders including …

Synaptic and neuronal loss are major neuropathological characteristics of Parkinson's
disease. Misfolded protein aggregates in the form of Lewy bodies, comprised mainly of α …

Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

The accumulation of the amyloid‐β peptides (Aβ) is central to the development of
Alzheimer's disease. The mechanism by which Aβ triggers a cascade of events that leads to …

Alzheimer's disease (AD) and Parkinson's disease (PD) are age-associated
neurodegenerative disorders characterized by the misfolding and aggregation of alpha …

Since its discovery, the study of the biological role of α-synuclein and its pathological
implications has been the subject of increasing interest. The propensity to adopt different …