T Cell Receptor Chain Centricity: The Phenomenon and Potential Applications in Cancer Immunotherapy

AA Kalinina, LM Khromykh, DB Kazansky - International Journal of …, 2023 - mdpi.com
T cells are crucial players in adaptive anti-cancer immunity. The gene modification of T cells
with tumor antigen-specific T cell receptors (TCRs) was a milestone in personalized cancer …

Of the multiple mechanisms leading to type 1 diabetes, T cell receptor revision may play a prominent role (is type 1 diabetes more than a single disease?)

DH Wagner - Clinical & Experimental Immunology, 2016 - academic.oup.com
A single determinant factor for autoimmunity does not exist; disease development probably
involves contributions from genetics, the environment and immune dysfunction. Type 1 …

Human Peripheral CD4+ Vδ1+ γδT Cells Can Develop into αβT Cells

H Ziegler, C Welker, M Sterk, J Haarer… - Frontiers in …, 2014 - frontiersin.org
The lifelong generation of αβT cells enables us to continuously build immunity against
pathogens and malignancies despite the loss of thymic function with age. Homeostatic …

Allelic exclusion of TCR α-chains upon severe restriction of Vα repertoire

V Rybakin, L Westernberg, G Fu, HO Kim, J Ampudia… - PloS One, 2014 - journals.plos.org
Development of thymocytes through the positive selection checkpoint requires the
rearrangement and expression of a suitable T cell receptor (TCR) α-chain that can pair with …

Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions

LE Higdon, KA Deets, TJ Friesen… - Proceedings of the …, 2014 - National Acad Sciences
Peripheral CD4 T cells in Vβ5 transgenic (Tg) C57BL/6J mice undergo tolerance to an
endogenous superantigen encoded by mouse mammary tumor virus 8 (Mtv-8) by either …

Revealing T-Cell Signaling States by 4-Dimensional Lattice Light-Sheet Microscopy of Receptor Dynamics

JN Rosenberg - 2021 - search.proquest.com
Lattice light-sheet microscopy provides large amounts high-dimensional, high-
spatiotemporal resolution imaging data of cell surface receptors across the 3D surface of live …

[引用][C] The specific antigen approach in multiple sclerosis: can it ever be enough?

DH Wagner Jr - Clinical Immunology (Orlando, Fla.), 2012 - europepmc.org
The specific antigen approach in multiple sclerosis: can it ever be enough? - Abstract - Europe
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