Bone mass increases progressively during childhood, but mainly during adolescence when
approximately 40% of total bone mass is accumulated. Peak bone mass is reached in late …

Background Idiopathic hypercalciuria is an inherited metabolic abnormality characterised by
excessive amounts of calcium excreted into the urine in patients with normal serum levels of …

Pediatric urolithiasis has increased globally in the last few decades. There has been a
change in the pattern of stone composition with an increase in the frequency of kidney …

Background Idiopathic hypercalciuria is an inherited metabolic abnormality that is
characterised by excessive amounts of calcium excreted in the urine by people whose …

Idiopathic hypercalciuria is a common disorder in children and can present with a range of
clinical presentations such as hematuria, voiding dysfunction, flank pain, abdominal pain …

Whether hypercalciuria is the result of a primary bone disorder, a consequence of a
persisting negative calcium balance or a combination of both still remains to be determined …

Background The incidence of nephrolithiasis in children and adolescents is increasing and
appears to double every 10 years. The most important role of the pediatric nephrologist is to …

In the past few decades pediatric urolithiasis has become more frequent. The reason for this
increase is not completely clear but has been attributed to changes in climate, nutritional …

Urinary excretion of calcium is the result of a complex interplay between three organs—
namely, the gastrointestinal tract, bone, and kidney—which is finely orchestrated by multiple …

Although idiopathic hypercalciuria (IH) is associated with reduced bone mineral density
(BMD), no studies to date have identified predictors of BMD change over an extended period …