During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …

The coronavirus membrane protein (M) is the most abundant viral structural protein and
plays a central role in virus assembly and morphogenesis. However, the process of M …

In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …

Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the
SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous …

Despite tremendous efforts, the exact structure of SARS-CoV-2 and related
betacoronaviruses remains elusive. SARS-CoV-2 envelope is a key structural component of …

The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 is
responsible for compaction of the∼ 30-kb RNA genome in the∼ 90-nm virion. Previous …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread
globally, and scientists around the world are currently studying the virus intensively in order …

Throughout history, coronaviruses have posed challenges to both public health and the
global economy; nevertheless, methods to combat them remain rudimentary, primarily due …

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and …

SARS-CoV-2 has been a pandemic threat to human health and the worldwide economy, but
efficient treatments are still lacking. Type I and III interferons are essential for controlling viral …